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Cutting Edge Technology for Gene Silencing
7 Oct 2010Sarah Sarah
Marketing / Sales
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Riboxx introduces a patented new generation of siRNA molecules for more effective gene knock-down. To maximise the success of experiments Riboxx also offers a unique Gene Silencing Guarantee service.
Riboxx has developed and validated a new structure of siRNA with a unique sequence motif. The Riboxx siRNA increases the efficiency of the gene silencing by enhancing loading of the antisense strand to the RISC complex. As a consequence, siRNA potency is increased, much less siRNA is needed for an effective knock-down with a subsequent reduction of off-target effects. In addition, the Riboxx siRNA displays a higher resistance to RNases in comparison to conventional siRNA such as blunt-end siRNA or siRNA with 3'-overhangs.
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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.