Creating diversity and novelty in drug discovery

5 Oct 2006

Product news

Zerenex Molecular™ has launched a new collection of over 4000 diverse and unique compounds within the Novel Chemical Entities - NCE™ collection.

These rare heterocyclic (small (hetero) cyclic (fused) ring compounds containing one or more chemical handles) including imidazoles, pyridines, pyrazines etc as well as a variety of alycyclic (piperizines, piperidines) and aromatic compounds will continue to assist medicinal and synthetic chemists globally in developing hit generation and hit-to-lead optimization libraries.

Using innovative chemistry, the company has designed, synthesized and acquired a variety of unique building blocks, key to creating diversity and novelty in drug discovery programmes.

Since its inception Zerenex Molecular™ continues to develop and strengthen its global reputation for specializing in the synthesis and supply of unusual small molecule compounds to the pharmaceutical and biotech industries.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.