Corning Introduces Corning® Spin-X® Ultrafiltration Concentrators

Corning Incorporated today introduced its Spin-X® ultrafiltration concentrators. The concentrators, available through Corning for the first time, utilize a vertical membrane design to provide researchers at academic, clinical, and pharmaceutical laboratories the ability to concentrate or desalt proteins with greater efficiency and recovery, minimize membrane fouling, and execute rapid ultrafiltration, even with particle-laden solutions.

“We have a long-standing reputation of providing our global customers with the laboratory equipment innovations they need to advance their respective research,” said Robb D’Amore, business director, Corning Life Sciences. “With the addition of our new Spin-X ultrafiltration concentrators, we are furthering our commitment to customers by expanding the breadth of our product offerings while meeting their increasing demand for fast and easy concentration, desalting, and buffer exchange to improve the quality and results of their protein- and biomolecule-based research.”

Key Features and Benefits include:
• Vertical membrane design that enables faster filtrations with minimal membrane blocking;
• Large membrane area, allowing for faster filtrations;
• Integrated dead-stop volume that minimizes the risk of concentrating to dryness;
• Low-binding materials that allow for high recovery;
• Graduations printed on the device providing convenience and accuracy;
• No re-spin necessary for easy handling; and
• Wide range of cut-offs and volume capacities, delivering solutions to meet all ultrafiltration needs.
Corning’s Spin-X ultrafiltration concentrators are currently available in three sizes, 500 µL, 6 mL, and 20 mL. Corning’s low-binding polyethersulfone (PES) membranes are available with five molecular weight cut-offs (MWCO): 5,000, 10,000, 30,000, 50,000, and 100,000. The Spin-X ultrafiltration concentrators can be used for multiple applications, including the concentration and desalting of proteins, enzymes, monoclonal antibodies, and immunoglobulins; removal of labeled amino acids; HPLC sample preparation; deproteinization of samples; recovery of biomolecules from cell-culture supernatants (lysates); and concentrating viruses from cells.