Corning Announces Extension to its HTS Transwell® -96 Permeable Support Products

18 Jun 2006
Kerry Parker
CEO

Product news

Corning Incorporated (NYSE: GLW), a global supplier of scientific laboratory and drug discovery products for more than 90 years, announced the addition of 3.0 µm, 5.0 µm polycarbonate (PC) membrane and 8.0 µm pore polyester (PET) membrane for its HTS Transwell -96 Permeable Support product line. These new, pore sizes allow chemotaxis and cell invasion assays in a higher-throughput format, enabling researchers to conduct assays in smaller volumes, test more samples in a single plate, and potentially conserve test reagents and compounds.

“In order for Trevigen, Inc. to provide a robust cell invasion assay system, we evaluated all 96 well plates that were commercially available to perform the assay. We determined that only the Corning plate met our specific product development needs and would satisfy the needs of our customers. The Corning plate was undoubtedly the clear choice for us to provide in our 96 Well BME Cell Invasion Assay kit,” said Jay George chief scientific officer, Trevigen, Inc. “Corning Life Sciences’ -96 Well is the best all-around for its reliability, large cell growth surface area, well constructed, and designed for easy manual or automatic usage and cost effectiveness.”

Corning HTS Transwell -96 Cell Migration Products provide Corning’s customers with a larger cell growth surface area, standard bar codes and an improved gripping surface. The new products are both automation and manual friendly, operating with easy-to-use media and cell access ports that facilitate efficient media sampling. Additionally, the Black Receiver Plate used for fluorescent read-out facilitates higher sensitivity by lowering the background, helping scientists be more precise in their experiments.

“Corning Life Sciences has made an ongoing commitment to continually enhance our products with innovative technologies that researchers require to save time and resources and maximize results,” said Lydia Kenton, business manager, Cells, Corning Life Sciences.

“Because cell and tissue techniques are becoming such an important part of life science research today, our customers were demanding new technologies that will take the existing methods of growing specialized cell types in an environment closely resembling the in vivo state to the next level. The introduction of larger pore inserts to our popular HTS Transwell -96 permeable support product offering clearly combines the best of proven methodologies with new innovation to ensure continued research developments.”

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.