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Collaboration to study potential drug delivery systems to live cells

Abcam plc
18 Dec 2019
Laura Sisman
Administrator / Office Personnel

Industry news

Abcam plc and SomaServe Ltd have announced a partnership to commercialize the cell delivery potential of the polymer-based PolyNaut® ‘bionic’ nanoparticles, which can carry a range of payloads directly to live cells.

Dr. Fran Crawford, CEO of SomaServe, commented: “Abcam’s reputation as an innovator in the field of biological reagents and dedicated global commercialization infrastructure, coupled with their transparent and collegiate partnership approach, made them the standout choice as our development and commercialization partner for the PolyNaut® Technology platform. We are excited to be working together to maximize the potential of our innovative delivery platform for research and diagnostic applications.”

Dr. Cheri Walker, SVP Corporate Development, Abcam, added: “Investing in innovative ideas and platform technologies and supporting these through to global commercialization, is a key element of our growth strategy. Our industry expertise and co-location in major technology hubs throughout the world, enables our partners to rapidly get their innovations into the hands of the global research community. Our objective is to partner, fund and commercializes early-stage technologies that have the promise to improve and accelerate research. And ultimately to contribute to advancing the understanding of biology and cause of disease, which enables new treatments and improved health outcomes.”

The collaboration will initially focus on the development and global commercialization of a suite of CelLuminate dyes, specifically created to revolutionize live-cell imaging by enabling cells to remain functional and viable for up to 14 days. This crucial reduction in toxicity gives users the ability to thoroughly probe and analyze their cells, enabling them to achieve deeper insights and advance their understanding.

Beyond improving and enhancing live-cell imaging, the team will work together to expand the delivery and assay options of the platform, including optimizing its potential in combination with antibodies and other technologies. In addition to the commercial partnership, Abcam has invested in SomaServe’s seed round to help accelerate the development of an innovative market-leading platform for research, diagnostic and therapeutic applications.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. ImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.Live Cell ImagingLive cell imaging is the study of living cells using microscopes and high-content imaging systems. This technique provides in-depth insight into fast and complex biological processes, by allowing dynamic imaging of living cells instead of acquiring an individual image at a single point in time.NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.

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