Clinical laboratory automation: Key considerations for your lab

Learn all about what it takes to achieve a fully automated clinical laboratory, as well as pre-purchase considerations with our clinical laboratory automation guide

31 Aug 2022
Taemur Daud
Associate Editor

Editorial article

How to buy: Clinical automation

Clinical laboratories of today are faced with increasing challenges, from staffing shortages to limitations in workflow caused by low-throughput processes. These issues and the gradual affordability of automotive systems have funneled laboratory diagnostics into a new age of clinical laboratory automation.

The shift is not without its challenges, however, with effective management, clinical laboratories are realizing the benefits of automation.

In this clinical laboratory automation guide, we look at how the automation of laboratory processes can be achieved using cutting-edge technology and principles such as Lean Six Sigma.

What is clinical laboratory automation?

Laboratory automation refers to the use of instrumentation to perform streamlined laboratory processes, requiring minimal human input.

Laboratory automated solutions eliminate or do away with the tedious elements of laboratory processing, which have typically been performed manually by clinical scientists or lab technicians. Increasing technology advances have gone further to provide automated solutions to more complex processes, effectively allowing the automation of whole workflows.

What are the benefits of clinical laboratory automation?

When done correctly, an automated laboratory can bring a whole host of benefits to an entire workflow. Some of the key benefits of clinical laboratory automation include:

  • Increased productivity – repetitive and time-consuming tasks are a thing of the past with automation. Lab staff can instead focus their time and energy on higher-level priorities while leaving manual operations such as sample labeling to robots.
  • Reduction in human error – tedious and repetitive tasks in a manual laboratory often cause several human errors. Automating tasks such as pipetting precise quantities of samples and data recording can ensure the accurate and error-free reporting of results.
  • Reduction in costs – laboratory automation can reduce the dependency of lab technicians, resulting in cost savings. Aside from productivity, waste can be reduced as automated robots are more accurate and efficient in using reagents.
  • Highly customizable – laboratory automation systems can be customized to suit the needs of a lab, maximizing workflow efficiency.

What are the different types of clinical laboratory automation?

The clinical laboratory automation guide details the different types and processes of automation that laboratory managers can utilize in their facilities. Each automation system is chosen for individual laboratories based on their demand and workflow.

Open vs closed automation systems

The preference for open or closed systems is a major consideration that lab managers must keep in mind, as each type can bring benefits and drawbacks depending on individual laboratories. An open automation system utilizes analyzers from different manufacturers, allowing laboratories to customize their tracks depending on their individual needs. A closed automation system uses analyzers that only work with equipment that are manufactured by the same company.

Total laboratory automation

The extent of automation in a laboratory can vary depending on the size and type of the laboratory. Some laboratories may favor a partial automation approach, where a selection of tasks is performed by robots while the rest are performed manually.
Conversely, an emerging trend is the gradual transformation of a laboratory to implement total laboratory automation (TLA), where tasks are unified on a single track. TLA presents the opportunity to achieve maximum efficiency for your lab. The clinical laboratory automation guide discusses this approach in detail, as it covers the methods and products required to achieve TLA.

How can Lean Six Sigma be applied to clinical laboratory automation?

A key management strategy covered in the clinical laboratory automation guide is the concept of Lean Six Sigma. This philosophy has been employed to great success in many different industries, and the story is no different when it comes to lab automation. A laboratory that incorporates Lean Six Sigma into its automation is one that is focused on delivering the most efficient results, both in terms of cost and speed. The clinical laboratory automation guide equips lab managers with important Lean Six Sigma principles, such as the elimination of waste and the improvement of flow.

Learn all about these principles and the steps you need to take to transform your lab into an automated utopia with our free downloadable clinical laboratory automation guide. This guide is essential reading for all clinical laboratory staff, including clinical laboratory managers, laboratory scientists and laboratory directors.

DOWNLOAD THE GUIDE TODAY

Frequently Asked Questions (FAQs)

What are the advantages and disadvantages of total laboratory automation?

Potential advantages of total laboratory automation include lower running costs in the long term, decreased congestion in the lab, improved efficiency and sample management, and more efficient integration of test results. Potential disadvantages include higher costs in the short term, infrastructure constraints, greater risk of downtime and the creation of possible bottlenecks.

What is the importance of automation in clinical laboratories?

Laboratory automated solutions eliminate or do away with the tedious elements of laboratory processing, which have typically been performed manually by clinical scientists or lab technicians. Increasing technology advances have gone further to provide automated solutions to more complex processes, effectively allowing the automation of whole workflows.

What is the definition of total laboratory automation?

Total laboratory automation (TLA) is the integration of automated analyzers onto a single track, such that specimens are processed and tested with minimal human input

Links

Tags

LIMSLIMS (Laboratory Information Management System) is an informatics software system used to improve the quality assurance and quality control (QA / QC) of data management. LIMS can be a standard for common lab workflows, such as commercial off the shelf systems (COTS), or customized for more specialized lab use. Systems are available for mainframe computers or PC.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Robotic WorkstationsRobotic workstations are automated platforms enabling the user to perform high-throughput, multi-application processes, from sample preparation tasks such as PCR set-up, DNA purification and NGS library preparation, to integrated sample prep and analysis workstations. Automation makes processes consistent, fast, precise and fully walk-away. Find the best robotic workstations in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Automation Supplies / AccessoriesAutomated accessories and consumables make lab processes fast, efficient and reliable. Useful automation accessories include microplate sealers, label printers and reagent reservoirs.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.3D Printing3D printing is becoming an increasingly popular fixture in modern labs. From making bespoke equipment and replacing broken parts, to fabricating biological structures that imitate natural tissue characteristics, 3D printers can be used for a broad range of applications. Laboratory ManagementLaboratory management involves overseeing the operations of a lab, ensuring compliance with safety regulations, optimizing workflows, and maintaining equipment. Efficient lab management is key to ensuring accurate results and minimizing downtime. Technologies like laboratory information management systems (LIMS) and automated lab equipment are helping labs streamline operations. Browse our peer-reviewed product directory to find the best laboratory management tools, compare products, read reviews, and get pricing directly from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Laboratory SafetyLaboratory safety is essential to the effective operation of all laboratories and is required to minimize the risk of harm during experiments. Guidelines, regulations, and equipment should be available in all laboratories to ensure that the working environment is safe and secure.Clinical AutomationClinical laboratory automation refers to the use of automated systems in clinical laboratories to increase efficiency, reduce human error, and improve patient care. From sample analysis to total laboratory automation, this plays a critical role in modern diagnostics and laboratory workflows. Explore clinical automation solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
Clinical laboratory automation: Key considerations for your lab