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Cleaver Scientific Focuses on Gel Electrophoresis at ArabLab 2016

Cleaver Scientific Ltd
24 Feb 2016
Alex Waite
Editorial Assistant

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Cleaver Scientific will be displaying its latest innovations in Gel Electrophoresis at ARABLAB 2016, to be held 20-23 March 2016 at the Dubai International Convention & Visitors Centre in the United Arab Emirates.

Visitors to Stand 354 will be able discuss and have a demonstration of electrophoresis and related products, including the revolutionary Safe” series of electrophoresis products, the OmniPAGE VS20WAVE-DGGE - a versatile Denaturing Gradient Gel Electrophoresis (DGGE) system and the new Horizontal Polyacrylamide gel electrophoresis (hPAGE) system.

The 'Safe' Series of products from Cleaver Scientific were designed to make DNA electrophoresis procedures safer, more convenient and more economical to run. Eliminating the need for Ethidium Bromide and UV light, runSAFE is a completely safe stain for DNA gel electrophoresis. runVIEW® is an innovative system which can be used to maximize the efficiency of DNA recovery from stained gels by minimizing the number of steps involved in post-electrophoretic purification. runDOC is a benchtop gel documentation system which sits above the gel tank and enable multiple real-time images of the process to be taken.

Modular in design the OmniPAGE VS20WAVE-DGGE system and its wide range of accessories allow laboratories to effortlessly switch between different mutation detection techniques, thereby maximizing throughput and screening efficiency. The system is compatible with microplates and thermal cycler blocks enabling 96-sample throughput which alleviates many of the bottlenecks associated with screening for DNA mutations.

The new hPAGE system’s horizontal format allows for a large number of samples to be run simultaneously and combines this with the greater resolution of polyacrylamide compared with agarose. A key advantage of the system is that it is very simple to pour and cast gels which takes away some of the complexity normally associated with vertical gel casting.

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hPAGE-SET

Cleaver Scientific Ltd

Cleaver Scientific announces the introduction of a horizontal polyacrylamide gel electrophoresis (hPAGE) system developed in collaboration with the Kirkhouse Trust, an organisation supporting research and education in the biological sciences.   Whilst vertical systems are commonly used for polyacrylamide gel electrophoresis, this newly developed unit’s horizontal format allows for a large number of samples to be run simultaneously and combines this with the greater resolution of polyacrylamide compared with agarose.  The model is based on the published work of Izzo et al (2006). The main advantage of the system is that it is very simple to pour and cast the gels which takes away some of the complexity normally associated with vertical gel casting.  

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omniPAGE Modular Systems

Cleaver Scientific Ltd

The omniPAGE range of Modular Vertical Gel Systems allow multiple electrophoresis techniques to be performed in the same unit. Using the same main tank and lid, three different inserts are interchangeable for slab gel, tube gel and electroblotting techniques.These systems are available in three size options, Mini 10 x 10cm, Mini Wide 20 x 10cm and Maxi 20 x 20cm and are available as individual, combination or complete modular systems. Combination and modular systems offer maximum value and space and have the added benefit of increased consistency which results from using the same universal base and lid.The systems include all modules and accessories required for Slab Gel Electrophoresis, 2-D Electrophoresis and Electroblotting. The central component is the omniPAGE Mini Vertical unit, Mini Wide Vertical Unit or omniPAGE Maxi Vertical unit. These include a rapid and intuitive casting system, enhanced and easy to set up cooling system and have increased capacity; they can run up to four gels per run. In addition, the omniPAGE Tube gel module is capable of resolving up to 10 first dimension gels and the Electroblotting module has a three blot capacity.

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Capillary ElectrophoresisCapillary electrophoresis (CE) is used to separate molecules based on charge, size and hydrophobicity. Pressure, voltage or a vacuum is used to introduce the sample to fused silica capillaries. Fluorescence, UV/Vis, UV or diode array detectors are used to visualize components. Types of CE systems include capillary electrochromatography (CEC), capillary zone electrophoresis and capillary gel electrophoresis. Find the best capillary electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.pH Meters and ElectrodesIon and pH meters are electrochemical equipment used to measure the pH (acidity or alkalinity) or specific ion concentration of a solution. Other meters can also measure the conductivity or dissolved oxygen content of a solution. pH meters, specific ion meters, conductivity meters and dissolved oxygen meters can come as benchtop or portable equipment. A meter’s electrodes can be replaced with easy to clean electrodes or electrodes for difficult media. pH, ion and conductivity meters are typically used in life science research, pharmaceutical testing, food and beverage, environmental and water analysis. Find the best pH meters and electrodes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Automation Supplies / AccessoriesAutomated accessories and consumables make lab processes fast, efficient and reliable. Useful automation accessories include microplate sealers, label printers and reagent reservoirs.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel ImagingGel imaging captures high-resolution images of electrophoresis gels to analyze DNA, RNA, and proteins. Essential in molecular biology, this technique helps visualize results for accurate quantification and documentation. Discover top imaging systems and compare user-reviewed options in our directory.ARABLABImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.MutationMutations are changes in the DNA sequence that can lead to diseases, including cancer and genetic disorders. Analyzing mutations is crucial in diagnostics, drug development, and personalized medicine. Explore mutation detection tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Cleaver Scientific Focuses on Gel Electrophoresis at ArabLab 2016