CLC bio Releases Desktop Software for Working with Genomics, Transcriptomics and Epigenomics

3 Feb 2011
Sarah Sarah
Marketing / Sales

Product news

CLC bio announces Version 4.5 of CLC Genomics Workbench - an update which gives molecular biologists access to analyze high-throughput sequencing datasets with powerful bioinformatics algorithms through a user-friendly graphical user-interface.

"Our RNA-seq analysis now supports the use of paired-end data for RNA-seq. A combination of single reads and paired reads can also be used, and expression values can now be stratified into transcript level expression values, both for single and paired reads, allowing users to compare two different samples across transcripts" elaborates Solution Delivery Manager at CLC bio, Søren Mønsted, and continues, "Another important new feature is our batching functionality of all our high-throughput sequencing tools, enabling researchers to perform the same analysis on several elements in one batch, which is an easy way to analyze multiple datasets in one go and thereby save time for setting up and running the same type of analysis multiple times.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.