Clarify and sterile-filter complex cell cultures in one step

16 Aug 2020
Georgina Wynne Hughes
Editorial Assistant

Product news

New innovation in a 24-well format for workflow improvements

Introducing the new AcroPrep 24-well filter plates for protein purification and 0.2 μm sterile filtration workflows. These new and innovative 24-well, 7mL volume, filter plates use unique combinations of Pall’s proprietary high-performance filter medias to clarify and 0.2 μm sterile filter. This provide time savings, high filter efficiency and streamlined workflow improvements.

Cell clarification and sterile filtration plate for protein purification workflows

Pall’s dual media clarification and sterile filtration AcroPrep 24-well filter plate can both clarify and 0.2 μm sterile filter in a single device and workflow step. The top layer features Pall’s Seitz® depth media and efficiently captures whole cells and cell debris. The lower Supor® EKV layer provides an efficient sterile filtration layer. The combination effortlessly recovers proteins from whole cell cultures with varying viabilities of up to 25M+ cells/mL in minutes using either a vacuum manifold or plate centrifuge.

0.2 μm filtration plate for sterile filtration workflows

Pall’s sterile filtration AcroPrep 24-well filter plate is well suited for plate-based sterile filtration needs such as for media, reagent, serum or proteins. Compatible with either a vacuum manifold or plate centrifuge, the filter plate utilies Pall’s Supor® EKV membrane which is a dual-layer PES 0.65 μm membrane integrated with a highly asymmetric 0.2 μm membrane for fast, efficient, and sterilizing grade filtration. The plate is tested to meet sterile Brevundimonas diminuta (Bdim) retention claims.

Discover more about the AcroPrep™ 24-well filter plates here >>

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.FiltrationFiltration and microfiltration are used to separate solids, particulates or large molecules from fluids (liquid or gases) in order to purify the filtrate. Explore a range of filter formats, including filter paper, plates and membranes for your separation needs. While larger particulates may be separated by gravity filtration, smaller particulates may require additional force for timely separation. Microfiltration equipment includes vacuum filters, as well as positive pressure, crossflow and centrifugal filtration devices. Find the best filtration products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Clarify and sterile-filter complex cell cultures in one step