Cisbio to Display Newest Innovations for Oncology Drug Discovery at AACR 2014

20 Mar 2014
Sarah Thomas
Associate Editor

Product news

Join Cisbio as they show you how they are “Building Better Assays” at the 2014 AACR Annual Meeting to be held April 5-9 in San Diego, California. The company’s commitment to provide novel assays, based on their patented HTRF® technology, to meet the evolving needs of oncology drug discovery researchers is reflected in the new products they are launching at this conference. Cisbio is excited to showcase their newest innovations at Booth #1748.

Cisbio will be introducing a number of new cellular assays at the conference. HTRF cellular phospho-protein and cell signaling assays provide precise, sensitive measurement of the level of phosphorylated and non-phosphorylated proteins that can be achieved in an endogenous cellular environment. All assays are based on the same sandwich immunoassay construction, comprising two specific monoclonal antibodies coupled to HTRF donor and acceptor dyes. Stop by their booth to learn more about their new HTRF cellular phospho-protein assays and their flexible implementation on the CyBi®-FeliX, a compact liquid handling platform, for an ideal automated cellular phospho-readout to simplify pathway investigation.

Cisbio will also be presenting their EPIgeneous™ products, a line of validated, HTRF assay kits and toolbox reagents for reliable, high throughput screening and investigation of epigenetic targets. Rapid advancements have been made in understanding the key role epigenetic modifications play in regulating cell activity and their implications on cell health and disease progression. This knowledge led to a growing interest in exploring epigenetic enzymes and proteins, such as histone methyltransferases (HMT), demethylases (HDMT), deacetylases (HDAC) and acetylases (HAT) as drugable targets. The newest additions to the Cisbio EPIgeneous product line for high sensitivity screening of epigenetic modifications, will be highlighted at the AACR Annual Meeting, including cellular epigenetic assays, a universal methyltransferase assay and epigenetic toolbox reagents.

Come explore the benefits of HTRF technology and see how Cisbio’s broad portfolio of fast and easy mix-and-read assays could simplify your life and dramatically increase throughput and productivity in your lab. Talk to them in person. Witness their technology in action. And experience what they mean by “Interaction Is Everything”. Click on the company website link to learn more about all of their new kits and reagents.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Epigenetic AnalysisEpigenetic analysis products are used to study heritable phenotype changes that do not alter the DNA sequence, such as DNA modifications affecting gene activity. Determine whether genes have been methylated with DNA methylation quantification kits or methylation microarrays. Assess epigenetic regulation with histone modification kits or ChIP-on-chip microarrays. Kits are also available for bisulfite conversion and amplification of your samples, as well as epigenomic library preparation kits for next-generation sequencing (NGS). Find the best epigenetic products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.AACRThe American Association for Cancer Research (AACR) is a leading organization focused on cancer research and treatment. It provides a platform for scientists, healthcare professionals, and industry leaders to share knowledge and collaborate in the fight against cancer.Olympics
Cisbio to Display Newest Innovations for Oncology Drug Discovery at AACR 2014