Chromatrap<sup>®</sup> Optimized Buffer Isolates High Quality Chromatin for ChIP

5 Jan 2017
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

Chromatrap® offers an optimized unique buffer chemistry that provides the leading solution for the isolation of high quality and high yield chromatin. The success of any ChIP assay is dependent upon the quality of your chromatin.

The unique buffer system for chromatin extraction developed by Chromatrap® has been cited in a growing number of recent publications including investigations into G-quadruplex structures in human regulatory chromatin and receptor signals in natural killer cells.

Chromatrap® has optimized products to enable you to prepare your chromatin using mechanical fragmentation (sonication) or enzymatic digestion. Offering both types of extraction kit gives you the flexibility of applying different methods to your research needs. Chromatrap® sonication shearing kit and Chromatrap® enzymatic shearing kit contain buffers for up to 10 chromatin preparations and guarantee the best quality chromatin from your samples.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.ChIP-SequencingDNA ExtractionDNA extraction is a critical step in many biological studies, including genomics, diagnostics, and forensic analysis. The process involves isolating DNA from cells or tissues, and the quality and purity of the extracted DNA can impact downstream applications. Explore DNA extraction products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.DNA MethylationChromatin
Chromatrap<sup>®</sup> Optimized Buffer Isolates High Quality Chromatin for ChIP