CELLINK launches an all-in-one imager and single-cell dispenser

UP.SIGHT™ is certified to help laboratories worldwide overcome major cell line development hurdles and improve efficiency across workflows

15 Mar 2021
Diane Li
Assistant Editor

Product news

cytena GmbH, a CELLINK company and leader in single cell dispensing technologies, launches the UP.SIGHT, a transformative single-cell dispensing system that increases efficiency in cell line development workflows. This all-in-one solution is equipped with cytena’s patented, fast and gentle single-cell dispensing technology and a rapid, high-quality imaging system that enables nozzle imaging and 3D Full Well Imaging (with no need for image stitching). It offers double assurance of clonality from two independent optical apparatuses and leads to a probability of clonality >99.99%.

“The UP.SIGHT represents a significant improvement in single-cell dispensing and the cell line development workflow,” says Erik Gatenholm, CEO of CELLINK. “Until now, the pharmaceutical industry has used a costly, time-consuming and wasteful process when isolating single cells for research purposes. Compared to existing single-cell dispensers, the UP.SIGHT is faster, more efficient and does it all in one device, while they require multiple devices. The UP.SIGHT is an example of the CELLINK Group’s commitment to bio-convergence and finding synergies in biology and engineering to create truly innovative technologies.”

Today, 8 out of the top 10 best-selling drugs worldwide are developed using biologics, and cell line development is an essential component of their production. The UP.SIGHT is the next generation of cytena’s single-cell dispensers and with high-precision cell deposition and imaging to ensure precise cell isolation and monoclonality. The UP.SIGHT streamlines cell line development so researchers can work faster and smarter. Additionally, cytena’s EASY.ON disposable cartridges eliminate the risk of cross-contamination and the need for extensive cleaning processes.

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Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.ImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.hiPS Cell Lines
CELLINK launches an all-in-one imager and single-cell dispenser