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Cellectricon Launches World’s First System for High Throughput RNAi Screening

Cellectricon
28 Mar 2008

Product news

Cellectricon, a leading provider of screening solutions for drug discovery, today announced the launch of the new Cellaxess® HT System. The world’s first fully automated high throughput transfection system enables reagent-free delivery of genetic material to a wide range of biologically relevant cell types. The system will be introduced at the SBS 14th Annual Conference and Meeting in St. Louis, MO, USA, April 6-10.

Cellectricon has developed Cellaxess®HT in close collaboration with leading research groups to meet the increasing demand for a technology capable of genome-wide RNAi screening.

"We are very pleased to meet the industry’s demand by bringing this state-of-the-art system to the market.” says Dr. Mattias Karlsson, CEO of Cellectricon. “Cellaxess®HT will revolutionize target discovery by opening the door to using more biologically relevant cell types in genome-wide RNAi screening.”

About the Cellaxess®HT system
Cellaxess®HT addresses the critical need for high throughput delivery of siRNA and cDNA to hard to transfect cells in several cell-based screening assays. Cellaxess®HT is the only fully automated system on the market allowing for high throughput transfection of cells in culture directly in 384-well microplates. The system enables reagent-free delivery to a wide range of biologically relevant cell types with excellent efficiency and viability at a throughput of 50 000 wells per day.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.

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Cellectricon Launches World’s First System for High Throughput RNAi Screening