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Cellectricon Launch the Cellaxess ACE for In-Situ Transfection at Neuroscience 2012

Cellectricon
22 Oct 2012

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SelectScience joined thousands of scientists at Neuroscience 2012 in New Orleans, USA to find out about the latest technologies that have been launched to facilitate neuroscience research. At the Cellectricon booth the Cellaxess® ACE, which enables high quality in-situ transfection of primary and iPSC-derived cells in their adherent state, was on show.

With the innovative Cellaxess® ACE, almost any cell type can be transfected at any stage of cellular development with virtually no impact on cell viability or morphology. In this aspect, the Cellaxess method is superior to cuvette electroporation and reagent-based methods.

The Cellaxess® ACE allows for long-term transfection and knock-down experiments, and gene expression can be detected up to several weeks after transfection in primary cell types. As cells can also be transfected at any stage of development, this allows for complete freedom in phenotypic studies.

Based on the same concept as Cellaxess® Elektra, the in-situ electroporation at low voltages results in transfections with unsurpassed efficiency and viability. Cellaxess® ACE enables transfection of any adherent cell type and is ideal for the transfection of challenging cell types, such as primary- and IPS derived neuronal cell types.

The Cellaxess® ACE can be used in variety of cell culture formats, ranging from 96-well plates to dishes. It is also an excellent match with high-content and microscopy readouts. It is available either as a complete system including pulse generator, or as a stand-alone module which can be combined with almost any pulse generator on the market, making it a highly cost efficient solution and an easy way to assess electroporation performance for low volume electroporation.

In addition the Cellaxess® ACE has an exchangeable capillary, which ensures sterility in experiments, as well as zero risk of cross contamination. Different capillaries can be utilized to accommodate for different cell culture formats.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.IpscTransfectionTransfection introduces nucleic acids (DNA or RNA) into cells, facilitating gene expression, genome editing, and functional studies. It�s widely used in genetic research, drug discovery, and therapeutic development. Find transfection reagents, kits, and systems in our product directory with reviews and pricing options.NeuroscienceNeuroscience research investigates the neurological mechanisms underlying behavior, neurodegenerative diseases, and other brain conditions. Learn about the innovative technologies for bioimaging, electrophysiology, cell culture, chromatography and other techniques used in this field.

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Cellectricon Launch the Cellaxess ACE for In-Situ Transfection at Neuroscience 2012