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Cellecta Announces Upcoming Presentations at AACR 2018

Cellecta

Presentations on novel developments in CRISPR screening technologies and applications for the DriverMap™ targeted RNA expression profiling assay

3 Apr 2018
Frankie MacDonald
Administrator / Office Personnel

Industry news

Cellecta, Inc. announced that it will deliver three scientific presentations at the upcoming American Association for Cancer Research (AACR) 2018 Annual Meeting, which will take place April 14-18, 2017 at the McCormick Place Convention Center in Chicago, Illinois. Cellecta researchers and an academic collaborator will present unpublished data on technology developments for genetic screens in human cancer cell lines using CRISPR-knockout, CRISPRi-repression, and CRISPRa-activation; as well as new data on application of the DriverMap targeted RNA expression profiling for drug screening and biomarker discovery.

Details of the presentations are as follows:

Spotlight Theatre Presentation: Genetic Profiling and Functional Screening for Drug Target and Biomarker Discovery

  • Date and Time: Monday, April 16, 2017, 10:00 – 11:00 a.m. Central Time
  • Location: McCormick Place Convention Center, Spotlight Theatre C – Exhibit Hall

The Spotlight Theatre will include the following presentations:

Efficient Tools to Enable Drug Target and Biomarker Discovery: A Brief Introduction to Cellecta Technologies – Paul Diehl, Ph.D., Chief Operating Officer, Cellecta

Optimization of CRISPR Technology for Large-Scale Genetic Screens – Sylvain Baron, Ph.D., Research Scientist, Cellecta

DriverMap™ Transcriptome Profiling: Applications in Drug Screens and Biomarker Discovery – Lester Kobzik, M.D., Professor of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Harvard School of Public Health

Poster Abstract LB-379/ Poster 7: Targeted single-cell RNA expression profiling for cellular characterization of the tumor microenvironment

  • Session: Late-Breaking Research: Molecular and Cell Biology
  • Date and Time: Wednesday, April 18, 2018, 8:00 a.m. - 12:00 p.m. Central Time
  • Location: McCormick Place Convention Center Exhibit Hall, Poster Section 45

Cellecta, a provider of genomic products and services, is an industry leader in RNAi and CRISPR technologies for the discovery and characterization of novel therapeutic targets, and genetic profiling for biomarker discovery. Cellecta’s functional genomics portfolio offers gene knockout and knockdown screens, custom and genome-wide RNAi and CRISPR libraries, cell engineering, RNAi and CRISPR construct services, targeted expression profiling, and biomarker discovery of disease samples. The DriverMap™ Human Genome-Wide Targeted Expression Profiling Assay enables researchers to simultaneously measure the expression level of almost 19,000 human protein-coding genes in a single assay.

Download Cellecta's Driver-MapTM expression profiling solutions brochure here

Links

CellectaCompany website

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Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AACRThe American Association for Cancer Research (AACR) is a leading organization focused on cancer research and treatment. It provides a platform for scientists, healthcare professionals, and industry leaders to share knowledge and collaborate in the fight against cancer.

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