CAS Enhances SciFinder® to Increase Productivity

9 Oct 2012

Product news

Chemical Abstracts Service (CAS), the world’s authority for chemical information, announced significant improvements to SciFinder, the choice for chemistry research™. The latest enhancements improve evaluation of reaction answer sets and allow easier collaboration with other SciFinder users.

Scientists can now group reactions in answer sets according to more than 500 commonly known reaction types, e.g. reduction of nitro compounds to amines. This feature will help in quickly examining the diversity of a large set of reactions. The feature organizes reactions the way chemists think, so synthetic options are apparent more quickly.

CAS also introduces a sharing feature for SciPlanner™, the interactive workspace in SciFinder that enables scientists to more quickly identify synthesis options. New SciPlanner import/export options make collaboration easier than ever by letting scientists share their workspace with other SciFinder users.

This update follows the progression of steady enhancements to SciFinder. In December 2011, CAS added substance relevance ranking and bioactivity and target indicator features to SciFinder to help chemists and biologists quickly access the information they need most. In February 2012, one-click access to commercial chemical source pricing and availability information enabled scientists to go directly from a substance search to a purchasing decision at the supplier’s site. Just two months later, SciFinder debuted features that improve search convenience, including searching of substance properties, converting CAS Registry Numbers® to structures, and previewing substance and reference answer sets with the in-context Quick View window.

CAS has also announced that SciFinder will be updated with nearly 200,000 additional experimental NMR spectra in the coming weeks. These experimental data will help scientists better characterize and identify substances.

“While we have a long tradition of enhancing SciFinder to meet the evolving needs of scientists, we also know that what sets SciFinder apart is the unparalleled content analyzed and curated by CAS’ global team of scientists with industry–leading timeliness,” said Chris McCue, vice president of marketing at CAS. “CAS covers more patent authorities than any other scientific information provider, and since 70% of new substances found in the literature are from patents, we are investing in new ways to present and manage substance and reaction information in SciFinder.”

SciFinder - Online Scientific Literature Search

Chemical Abstracts Service (CAS)

CAS SciFinder -  The First Choice With SciFinder from CAS, you can increase your productivity and achieve faster breakthroughs Advancing the pace of research, Chemical Abstracts SciFinder search allows you to get results fast without compromising precision and accuracy. CAS SciFinder allows you to explore a wealth of information using sophisticated search and analysis technology. Chemical Abstracts SciFinder is a research discovery tool that allows you to explore the CAS databases that contain literature from many scientific disciplines, including biomedical sciences, chemistry, engineering, materials science, agricultural science, and more! Be more productive in your research process • CAS SciFinder provides easy access to the highest-quality and most comprehensive collection of chemistry and related scientific information from the CAS databases. • SciFinder's streamlined navigation and intuitive and secure interface make it simple to quickly find the right information to support your research.

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NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Labware and Lab SuppliesLabware and lab supplies include various forms of glassware, plasticware, reagents and personal protective equipment (PPE) and are used across all scientific laboratories, enabling daily tasks to be performed. Explore a range of flasks and beakers, petri dishes, carboys and storage bottles. Labware such as condensers, desiccators and burettes are also available for more specific tasks. Find the best labware and lab supplies in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Data MiningData mining is an important process for extracting information, patterns and trends from data. Data mining software, databases, reference materials and storage packages are available to process lab data.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.