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Cambridge Research Biochemicals adds QuickAllAssay™ Lanthanide labeling reagents to its product range

14 Feb 2013

Product news

Cambridge Research Biochemicals (CRB) has signed an exclusive deal with Bio-Nobile (BN) Products and Services (Finland) to promote and sell QuickAllAssay™ labeling reagents in the UK. The ready-to-use reagents are used for labeling of proteins, antibodies and small molecules with a Europium chelate and are unique in that only one kit is required for labeling all assay formats including TR FRET (Time-Resolved Fluorescence Resonance Energy Transfer) and QRET (Quenched Resonance Energy Transfer assays) and for separation based enhanced time-resolved fluorescence assays.

The QuickAllAssay™ kit offers researchers looking to quantify biochemical markers a number of significant advantages over traditional assay technology. Separation based TRF assays, also known as Dissociation-Enhanced Lanthanide Fluorescent Immunoassays (DELFIA) are popular for research, as they offer a superior alternative to traditional ELISA technology as they are significantly more sensitive, have a broader dynamic range and are more robust than enzyme-based assays.

The QuickAllAssay™ kit can offer dual and triple label separation based (coated plate) assays which are now routinely being used by screening laboratories. Lanthanides are now the perfect choice of label with which to build such assays as they offer the unique possibility of building multi-label measurements within the same well.

“We are delighted to now be able to offer QuickAllAssay™ to our UK customers,” comments Emily Humphrys, Commercial Director from CRB. “We believe having a unique kit for both homogeneous and separation assays which is significantly more sensitive and has a broader dynamic range in one easy-to-use kit will be of significant benefit to researchers. We are also able to offer custom Europium labeling of peptides, proteins and antibodies, which further broadens our labeled product offering.”

CRB is a leading manufacturer and supplier of specialist custom peptides and antibodies and works with some of the largest pharmaceutical companies and research organizations in the world. The company is renowned for its high-level of customer support, help and advice and is able to identify in advance products that they would like to have made available to them such as the QuickAllAssay™ kit.

Ilkka Hemmilä, Chief Scientific Officer from Bio-Nobile (BN) Products and Services of Finland, the original inventor of the DELFIA and LANCE assay technologies declared, “I am pleased to be partnering with Cambridge Research Biochemicals, which has a well-established peptide chemistry, labeling and antibody reputation and believe this collaboration will lead to future novel technologies and applications to benefit the screening market.”

DELFIA and LANCE are registered trademarks of Perkin-Elmer

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.LabelingConjugationTR-FRETImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.

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Cambridge Research Biochemicals adds QuickAllAssay™ Lanthanide labeling reagents to its product range