Calbiochem® TruLight Kinase Assay Kits
8 Nov 2008Product news
Superquenching Increases Kinase Assay Sensitivity.
TruLight™ Kinase Assay Kits and the TruLight Universal Kinase/Phosphatase Assay Kit provide a new technology for rapid, sensitive detection of enzyme activity. The assays are also convenient for high-throughput inhibitor screening. Unlike FRET or traditional fluorescence quenching assays, where quenching is equimolar between donor and receptor, TruLight assays use polymer superquenching, which results in assays that are up to 10 times more sensitive. In addition these kits do not require special equipment, radioactive materials, or secondary (detector) enzymes or antibodies.
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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.