Bruker Daltonics Launches Unique ImagePrep™ Matrix Deposition Device for MALDI Molecular Imaging in Biomarker Discovery, Drug Imaging and Pathology Research

20 Sept 2007
Greg Smith
Analyst / Analytical Chemist

Product news

Bruker Daltonics launched its ImagePrep™ sample preparation device for automated matrix deposition onto tissue slices. MALDI mass imaging of tissue samples with Bruker's MALDI Molecular Imager (for research use only) solution allows color-coded visualization of the distribution of peptide or small protein biomarkers, or of drugs and their major metabolites for the direct analysis of molecular distributions in tissue sections.

The new ImagePrep device provides highly reproducible sample preparations for MALDI Imaging in a fully automated, push-button process. Another unique advantage of ImagePrep is the combination of excellent spectra quality at high image resolution of 50 micron at the same time.

With the launch of the ImagePrep, Bruker completes its MALDI Molecular Imager solution consisting of autoflex™ or ultraflex™ high-performance MALDI-TOF(/TOF) mass spectrometers with smartbeam™ laser technology and PAN™ panoramic mass resolution over a broad mass range, plus flexImaging™ software for data analysis, visualization and statistical analysis of MALDI images, including the proprietary ClassImaging™ method for the molecular imaging equivalent of diagnostic multimarker panels.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. MALDI-TOF MSMALDI-TOF mass spectrometers (matrix-assisted laser desorption/ionization time-of-flight) are used for the mass analysis of large molecules, including proteins, DNA, polymers and other macromolecules due to its relatively soft ionization, reducing fragmentation whilst allowing fast data acquisition. Tandem mass analyzers such as TOF/TOF systems can be used to increase resolution and sensitivity of your analysis. Find the best MALDI-TOF products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.