Brooks Life Science Systems Launch the Plate Auditor for Automated Compound Quality Control

24 Sept 2012

Product news

Brooks Life Science Systems, a division of Brooks Automation, Inc., a leading worldwide provider of automation solutions for compound and biological sample storage and management, has announced the commercial launch of the Brooks Plate Auditor™, a fast, accurate and non-invasive tool for identification of precipitate and empty wells in compound and screening plates. The new Plate Auditor is the result of a successful collaboration with the Scripps Research Institute.

The new Plate Auditor is designed to evaluate the quality of microplate-based compound samples for precipitation and liquid volume prior to use in compound management and high throughput screening activities. The system rapidly analyzes plates to automatically verify sample integrity thus eliminating the need for extensive manual quality control.

“The contents of a plate are a fingerprint for all of the potential problems you encounter in a Compound Management operation; Plate Auditor allows easy and rapid detection of many of those problems using machine vision and sophisticated image processing”, stated Peter Hodder, PhD, Senior Director and Head of Lead Identification at the Florida campus of Scripps Research. The ability of the instrument to provide sample color information makes the Plate Auditor a unique option for monitoring sample quality over time, and identifying wells with artifacts which may interfere with or invalidate screening results.

Plate Auditor joins Celigo® Imaging Cytometer and Tube Auditor™ instruments as part of Brooks’ growing range of vision-based research instruments that analyze compounds, biological samples and adherent/non-adherent cells.

The Plate Auditor is being showcased at the MipTec Drug Discovery Conference, 24-27 September 2012, in Basel, Switzerland. Data highlighting how Plate Auditor enhances compound testing integrity was presented at the recent IQPC Compound Management and Integrity Conference, in Boston, MA, US.

In February 2012 Brooks announced the collaboration with the Scripps Research Institute to develop and commercialize the Plate Auditor instrument. “We are delighted to have worked with the Scripps Research Institute’s compound management group to bring the new Plate Auditor so rapidly to the market,” commented John Lillig, Senior Vice President and Managing Director of Brooks Life Science Systems.

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.MipTecPrecipitate Identification