Boreal Genomics Secures $18 Million Series C Financing to Expand Commercial Operations in Life Science Research Market and Launch Clinical Application for Non-Invasive Tumor Profiling

7 Oct 2013
Sarah Thomas
Associate Editor

Product news

Boreal Genomics, a privately held provider of technology for non-invasive genomic profiling of tumors from blood plasma of cancer patients, announced today the completion of an $18 million Series C financing round. The financing will be used to expand commercial operations in the translational research market, scale laboratory capabilities and launch clinical applications for non-invasive genomic profiling and monitoring of cancer.

The financing includes existing investors ARCH Venture Partners, Kearny Venture Partners and new undisclosed strategic and private investors.

Boreal’s OnTarget platform performs highly sensitive genomic analysis of cell-free DNA in plasma to detect and quantify mutations in tumor-derived circulating nucleic acids. The OnTarget assay uniquely addresses the requirements for a successful blood-based cancer diagnostic by combining single molecule sensitivity, high specificity and multiplexing across many targets into a single test. Boreal currently provides the assay through both service and instrument offerings for research use only, and expects the test will soon be certified for use in clinical studies. The company is also expanding their Bay Area facilities, including laboratory and commercial operations at a new location in Mountain View, CA.

Our OnTarget platform is commercially available and has been successfully used by customers in translational research to perform genomic profiling of solid tumors from blood, said Nitin Sood, Chief Executive Officer of Boreal Genomics. “With the financial and strategic support of our investors, we will continue our expansion into the life science research market and launch clinical applications aimed at improving the standard of care for cancer patients through routine blood-based testing.”

“In the rapidly growing field of non-invasive liquid biopsies, Boreal has developed powerful technology and we look forward to supporting the company’s continued commercial acceleration, said Keith Crandell, Managing Director at ARCH.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.
Boreal Genomics Secures $18 Million Series C Financing to Expand Commercial Operations in Life Science Research Market and Launch Clinical Application for Non-Invasive Tumor Profiling