SelectScience
Join Free
Accelerating Science
NewsLife Sciences

BMG LABTECHS´s PHERAstar Plus sets new standards in HTRF<sup>®</sup> , luminescence and fluorescence polarization reading

BMG LABTECH
18 Mar 2008

Product news

To satisfy the ever-increasing demands of the HTS community a new version of the highly successful microplate reader PHERAstar is available from BMG LABTECH, the PHERAstar Plus. The PHERAstar Plus features Advanced HTRF® / TR-FRET, Advanced Luminescence, and Advanced Fluorescence Polarization reading modes by integrating the latest technological advancements in optics and electronics. Coupled with the new powerful data analysis software package MARS, these new features extend the application versatility of the PHERAstar Plus.

The PHERAstar Plus is a simultaneous dual emission HTS microplate reader offering all leading detection technologies including fluorescence intensity / FRET, fluorescence polarization, time-resolved fluorescence / TR-FRET, laser-based AlphaScreen®, luminescence / BRET, and UV/Vis absorbance. The new instrument provides both enhanced HTRF® performance with market leading Z’ and TR-FRET ratio performance and a fourfold increase in luminescence sensitivity. This is made possible by BMG LABTECH’s innovations in the modular optical system combined with the unique well-proven detection technology. The PHERAstar Plus is the only microplate reader on the market with five photomultiplier tubes (PMTs) and Simultaneous Dual Emission (SDE) technology optimized for specific reading modes and the capability to capture TR-FRET decay curves in real-time for assay optimization.

The PHERAstar Plus will be delivered with a new version of BMG LABTECH’s established Reader Control and a completely new MARS Data Analysis Software with significant ease-of-use enhancements such as S/N, Z’, and many other standard calculations. The Wizard creates an easy step-by-step calculation of a standard curve and the Template Manager is an excellent tool for building complex data processing protocols. Thus, user-defined data analysis is done simply with one click of the mouse. Improved robotic integration capabilities, digital signature and the 21 CFR part 11 compliance of MARS complete this new software.

Links

BMG LABTECHCompany website

Tags

High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

Related articles