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BMG LABTECH Supports Four iGEM Teams to Fund Undergraduate Research Competition

BMG LABTECH

Synthetic biology projects receive high performance microplate readers

22 Aug 2016
Finn Price
Administrator / Office Personnel

Industry news

BMG LABTECH recently supported four iGEM teams with a microplate reader to fuel their participation at the annual iGEM competition. The teams will compete at the iGEM Giant Jamboree held at the Hynes Convention Center in Boston, attended by 300 teams from around the world.

“Supporting the iGEM teams is a reflection of BMG LABTECH’s commitment to scientific education. The ideas and research approaches developed by this challenge are giving hope to push the synthetic biology to new levels,” says Tobias Pusterla, the company’s International Marketing Manager. BMG LABTECH is pleased to offer a microplate reader to the teams of the University of Freiburg (Germany), the Imperial College (UK), the Manchester University (UK) and the Newcastle University (UK).

The four teams work all summer long on their novel and exciting projects in synthetic biology. The group at the University of Freiburg is using the CLARIOstar® microplate reader to develop a method combining the specificity of antibodies and the durability of nanoparticles in a single application. The team’s aim is to find an ability to target specific disease-associated cells while not affecting their surroundings and healthy tissues by distributing medication throughout the whole body.

The Imperial College in London constructed a project which could be from further importance for future iGEM teams, using the FLUOstar® Omega microplate reader. Their aim is to develop a framework with co-cultures to provide a standardized approach that enables to spread complex circuits and pathways across multiple microbial populations. Moreover, they want to demonstrate the effectiveness of the system by applying it to a critical challenge, such as renewable chemical and material production, waste treatment, or bioremediation.

The iGEM team at the Manchester University has chosen a project to prevent and reduce undesired consequences of alcohol consumption. The group is working with a FLUOstar® Omega microplate reader to develop an alcohol patch which generates a visible color change according to blood alcohol concentration. Based on the knowledge that the ethanol concentration in sweat is linearly related to the blood alcohol concentration, the aim is to create an ethanol biosensor by using synthetic biology with two separate methods to measure intoxication levels.

The success of Newcastle’s iGEM team, with the production of a functional circuit, will provide the foundation for a new breed of science, fusing together biological and electronic technologies. The FLUOstar® Omega microplate reader is used to build a circuit that allows synthetic biologists to combine bacterial and electronic components to create electro-biological circuits, offering an exciting new fusion of synthetic biology and computer science.

BMG LABTECH is at the forefront of microplate reading technology, its products offering many types of bioanalytical measurement techniques including fluorescence intensity, fluorescence polarization, luminescence, time-resolved fluorescence, UV/Vis absorbance, AlphaScreen®, and nephelometry. All microplate readers are manufactured and tested at BMG LABTECH’s headquarters in Germany, which guarantees their precision, reliability, and robustness.

The iGEM competition is an annual, worldwide, synthetic biology event aimed at undergraduate university students, as well as high school and graduate students. At the Giant Jamboree, iGEM teams compete for various awards. These awards range from Medals to Track Awards to Special Prizes for the finalists. The three finalists will be selected based on their overall excellence of their entire project, from choice of project, presentation, to the success and impact of the project, to consideration of issues of Human Practices.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.NanotechnologyNanotechnology, or nanotech, is an engineering technique using molecular scale functional systems. Applications of nanotechnology include medicine and medical devices, electronics, air and water purification, food science and energy production.Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.Research and DevelopmentNanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.

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BMG LABTECH Supports Four iGEM Teams to Fund Undergraduate Research Competition