BioTek Instruments Expands Microplate Washing Product Line with ELx50™ Filter Microplate Washer

12 Apr 2007

Product news

BioTek Instruments, Inc. today announced the expansion of their popular microplate washing product line with the launch of the ELx50™ Filter Microplate Washer (FMW). Based on the proven technology of BioTek's automated 8-channel ELx50 strip washer with over 7,000 instruments sold, the ELx50 FMW features a syringe drive fluid-delivery system with an automated vacuum filtration solution for unattended processing of 96-well filter bottom plates.

Unlike solid bottom microplates, filter microplates must be aspirated from below instead of above to maintain the integrity of free-floating or loosely adherent materials within the microplate wells. Manual methods to wash filter microplates, including vacuum manifolds, are often inconsistent and cannot be adjusted to accommodate different fluid viscosities. The ELx50 FMW automates the process for consistent wash performance with improved %CV's. Its unique aspiration carrier may be adjusted for optimal performance with a variety of filter pore sizes from 0.45 µm to 1.2 µm, fluid viscosities and plate designs. These features are important during vacuum filtration-to-waste processes such as PCR cleanup after DNA amplification, and especially valuable when using multiplex microsphere assay technology.

"Interest in multiplex bead assay platforms using filter microplates, such as the Luminex xMAP® technology, is growing because these assays provide increased throughput in higher density formats with a high degree of accuracy and reproducibility," remarked Jason Greene, BioTek Product Manager. "The ELx50 FMW is paramount to this assay format, providing critical levels of accuracy, reproducibility and convenience that just aren't possible with manual wash methods."

Additionally, the ELx50 FMW's modular platform allows for programmable and automated processing of standard solid bottom microplates used in many traditional ELISA and cell-based assays.

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ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
BioTek Instruments Expands Microplate Washing Product Line with ELx50™ Filter Microplate Washer