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BioTek Highlights Microplate Reader, Washer/Dispenser Technologies and More at SBS 2009

Agilent Technologies
14 Apr 2009
Samantha Rosoman
Campaign Coordinator

Product news

BioTek Instruments, Inc., will present their latest advancements in microplate instrumentation technologies at the 15th annual Society for Biomolecular Sciences Conference & Exhibition, booth 152. The exhibition will be held April 26-30, 2009 at the Lille Grand Palais in Lille, France.

Featured at the BioTek booth will be the new modular, monochromator-based Synergy™ Mx Multi-Mode Microplate Reader with Ultra Fine-Tuned™ performance. This reader provides fluorescence, luminescence and absorbance results on par with that normally found only in dedicated single-mode systems. The top- and bottom-read fluorescence system is fully monochromator-based and equipped with a variable bandpass selection system for added flexibility, while premium quadruple grating architecture guarantees and exquisite level of spectral discrimination and smooth spectral scans.

Also on display, the new EL406™ 1536-well Combination Microplate Washer Dispenser offers fast and efficient microplate washing and dispensing in 1536-well microplates as well as 96- and 384-well microplates. By combining microplate washing and up to three reagent dispensers, researchers no longer need to purchase and maintain separate instruments for each assay wash and reagent dispense step. Accurate and precise dispensing is available from peristaltic and microprocessor-controlled syringe drive reagent dispensing technologies. It’s also BioStack™ Microplate Stacker compatible and controlled via LHC™ Software or the instrument’s onboard keypad.

The EL406 will also be featured in the tutorial, “Improving the Performance of Wash Assays in 96-, 384-, and 1536-well Densities”, presented at the conference Monday April 27 from 1:45 to 2:30pm in the Charles de Gaulle room.

BioTek’s technical poster presentations at SBS 2009 include:

• Automation of Predictor™ hERG Fluorescence Polarization Assay Using Precision™ Automated Pipetting System for Serial Dilution of Small Molecule Drugs for IC50 Determinations
• Automated ApoTox-Glo Multiplexed Assay to Simultaneously Assess Cell Viability, Cytotoxicity and Apoptosis
• Bacmam-enabled Cellular Assays Measuring Histone Post-translational Modifications
• Optimization and Validation of a High-throughput Time-Resolved Fluorescence (HTRF) Assay for Inhibitors to Class IA Phosphoinositide 3-Kinase Isoform Activity
• Multiplexed GPCR Assays using HTRF® Technology
• Automated ELISA Liquid Handling with EL406™ Combination Microplate Washer Dispenser
• Automation of Luminescence-based CYP Inhibition Assays for Use in Drug Discovery

Also featured at the BioTek booth are BioStack™ automation modules, which can be connected to BioTek’s microplate instruments for increased speed, flexibility and ease of operation, and Precision™ XS Microplate Sample Processor, with four distinct liquid transfer tools in one compact platform.

Details on BioTek’s products and technologies are available at Booth #152

Related products

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Agilent BioTek BioStack Microplate Stacker

Agilent Technologies

The Agilent BioTek BioStack microplate stacker is a compact and versatile microplate stacker, compatible with Agilent BioTek washers, dispensers, plate readers, and imaging systems. The rapid plate exchange speeds deliver increased throughput and enhanced efficiency and greater productivity.

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Agilent BioTek Liquid Handling Control (LHC) Software

Agilent Technologies

Agilent BioTek Liquid Handling Control (LHC) software is a powerful yet flexible interface for use with Agilent BioTek washers, dispensers, and combination liquid handling systems. LHC software makes it easy to program even the most complex protocols with a choice of deployment. These protocols can be run directly from the computer or downloaded to the instrument for convenient onboard recall and operation.

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.

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