Biorelate offers free access to AI-based drug discovery tool: Galactic

The platform aims to help researchers generate a clearer view of the current state of research and gain invaluable insights

27 May 2020
Diane Li
Assistant Editor

Industry news

Biorelate, a UK-based AI start up, is offering all researchers free use of Galactic, its cloud-based web tool, to support biomedical research while lab access is restricted around the world.

Systematically analysing the data available on targets, drugs and disease mechanisms from data repositories and academic papers takes researchers over a year on average. The cognitive computing platform behind Galactic (Galactic-AI™) can speed up the research process by collecting and curating more than 30 million biomedical research text sources. With up to 80% of biomedical data thought to be unstructuredi, the platform helps researchers to generate a clearer view of the current state of research and gain invaluable insights.

In an open letter to cancer researchers, Cancer Research UK noted: “Universities are partially closed, laboratories have wound down their activities, experiments have stopped. Researchers are continuing to work productively from home, writing papers, analysing data, pulling together collaborations, reading the literature and generating ideas. But the progress of research will slow down, and this will inevitably have an impact on researchers’ careers and the lives of people affected by cancer.”

Dr. Daniel Jamieson, CEO and founder of Biorelate, commented: “As so many scientists focus on COVID-19, a serious risk is that research into other diseases grinds to a halt. Our platform auto-curates knowledge, helping researchers across all disease areas make better use of all the existing and emerging scientific data locked away in text. We very much hope that with the release of Galactic, a browser-ready search engine to our platform, researchers will be able to take advantage of potential insights into focal points of research, such as drug targets and indications, at a time when they are more limited to desk-based activities.”

Kevin Cox, Chairman of Biorelate, added: “We believe that Galactic has an important role to play in helping those involved in drug discovery to continue their research and ensure we get new therapies to patients without delay. We’re pleased to be offering free access to the Galactic web app at a time when researchers are in desperate need of this kind of resource and support. We have had very positive feedback from early adopters, who are using the tool to find causally related data and perform systematic and pragmatic reviews.”

Users of the Galactic web tool can navigate Galactic’s tailored portals to find research, experts, organisations and hidden insights – such as causal interactions – and make hypotheses and predictions while saving significant time and resources. The tool also offers more technical functionality for large enterprises who want to input their own textual content and ontologies they’ve designed in house.

For more data science or informatics-led activities, Biorelate offers direct access to curated data from the platform, to provide, for example, novel causal interactions that can be used to investigate biological pathways and study the impact of drugs on specific disease models. Biorelate also offers bespoke services in using the platform, Galactic-AI™, in combination with data science expertise to help solve and answer important drug discovery questions. Their experts put together evidence and rationale and bridge the gaps in a customer’s understanding of targets/indications to guide their clinical strategy.

To access the free Galactic tool, register here: https://bit.ly/2X3fDvp

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Molecular Recognition SoftwareMolecular recognition software is widely used to analyze DNA, RNA, proteins and chemicals. The software can be useful for graphical viewing, comparative analyses, high-throughput screening, genomics, proteomics and phylogenetics. Molecular recognition software uses bioinformatics tools and analyses such as BLAST searches and generates structural predictions, 3D structures and sequencing information.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. 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Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. Development SoftwareComputational techniques used in both the chemistry and biology aspects of drug development, for data acquisition, data analysis, processing and storage. Software is used for analysis of ADME results, toxicology, clinical trials and regulatory processes. Cancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.Cloud Based SoftwareCoronavirusCoronaviruses are a large family of viruses that can cause illnesses ranging from the common cold to more severe diseases like COVID-19. 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Biorelate offers free access to AI-based drug discovery tool: Galactic