SelectScience
Join Free
Accelerating Science
NewsLife Sciences

Bioplex Manager 5.0 Software Brochure Is Now Available

Bio-Rad
4 Feb 2008

Product news

Bio-Rad Laboratories, Inc., a multinational manufacturer and distributor of life science research and clinical diagnostic products, announces the availability of product brochure (bulletin 5613), which describes the latest BioPlex® Manager 5.0 software.

About BioPlex
The Bio-Plex® suspension array system is a flexible and easy-to-use multiplex analysis system that allows for simultaneous analysis of up to 100 different biomolecules (proteins, peptides, or nucleic acids) in a single microplate well. By multiplexing with the Bio-Plex suspension array system, researchers can dramatically increase the amount of useful information they can obtain from rare or volume-limited samples such as mouse or rat serum. In addition, they can decipher complex interrelationships among proteins involved in signal transduction pathways. The microplate platform allows the automated analysis of 96-well plates with a throughput of more than 1,800 assay points – for a 23-plex assay – in 30 minutes.

The Bio-Plex suspension array is built around three core technologies. The first is the family of fluorescently dyed microspheres (beads) from Luminex Corp. The second is a flow cytometer with two lasers and associated optics to measure biochemical reactions that occur on the surface of the microspheres, and the third is a high-speed digital signal processor to efficiently manage the fluorescent output. These technologies are brought together in the Bio-Plex workstation.
The Bio-Plex suspension array system integrates assay kits, software, calibration and validation tools, and instrumentation into a complete system, which is complemented by customer support.

About BioPlex Manager 5.0 Software
Bio-Plex Manager 5.0 software offers new features that extend the power and analysis capabilities of the Bio-Plex® suspension array system. New features enable:

A new graphing capability to quickly compare sample data and results between samples and across analytes, allowing users to better understand the data using a customizable graph.

An automated maintenance feature that allows researchers to set up and automatically run (unattended) “pre” or “post” run custom maintenance and shut-down operations. This feature permits users to use their time more productively as the system can be programmed to run all maintenance protocols using the Bio-Plex system reservoir.

Data normalization that uses internal controls such as housekeeping genes or external/exogenous controls, which allow users to establish a comparison parameter and increase their confidence in their results .

A new multiple analyte table layout for viewing sample data across analytes within a single view. This feature allows users to scroll through the entire results data set and hide columns as needed, providing an excellent way to visually compare results.

Bio-Plex Manager software can be used with any xMAP technology assay from Bio-Rad or any other provider. Bio-Plex Manager software supports Luminex 100 and 200 series instruments and all xMAP technology bead types, including magnetic beads. Several upgrade kits are also available to users of previous versions of Bio-Plex Manager software (3.0, 4.0, and 4.1) and to users of software from other vendors.

Availability
Bulletin 5613 is available either from a local Bio-Rad sales office or it can be downloaded from the Bio-Rad Laboratories web site accessed via the article webpage. There you can download a presentation of Bio-Plex Manager Features.

Links

Bio-RadCompany website

Tags

MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.

Related articles