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Biopharmaceuticals webinar series: Explore the latest trends in biopharmaceutical research and development

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In this series of webinars, discover the latest techniques and technologies helping researchers advance their biopharmaceuticals workflows

16 May 2021
Edward Carter
Publishing / Media

Expert insights

Benefit from live presentations from experts in the field, take part in interactive Q&A sessions, and download related resources to supplement your own biopharmaceutical research

In this series of webinars, explore the latest trends in biopharmaceutical research and development. Discover the techniques and technologies helping researchers improve tumor-specific immunotherapies, simplify complex characterization of large molecules, optimize oligonucleotide analysis, ensure regulatory compliance and data integrity, and much more.

Register by clicking on the live events below to hear from biopharma experts. Ask the speakers your questions in the live Q&A sessions following each presentation. Plus, check out a selection of our on-demand webinars and download related resources to supplement your own research.

Large molecules get SLIM: High-Resolution Ion Mobility for simplifying complex large molecule characterization

Now available on demand

Dr. Jim Arndt, from MOBILion, and Dr. Jeffrey Agar, Associate Professor at Barnett Institute Northeastern University, will discuss the benefits of HRIM-MS for enhancing structural characterization of large molecule therapeutics, while increasing throughput and reducing reliance on LC-based methods.

Register here

Quantifying T cell exhaustion: An insight into BiTE antibodies and CAR-T cells for improved therapeutics

Thursday, May 20, at 16:00 BST / 17:00 CEST / 11:00 EDT / 8:00 PDT

T cell exhaustion is recognized as a major challenge in the development of immuno-oncology therapies. It describes the loss of effector function due to chronic antigen exposure, and often occurs within the tumor microenvironment, impairing the ability of T cells to eradicate cancerous cells effectively. In this webinar, gain unique insights into how bispecific T cell engager (BiTE) antibodies in an immune cell killing assay affect T cell exhaustion; explore the influence of target cells on CAR-T cell exhaustion; and learn how to use an advanced flow cytometry platform to quantify T cell exhaustion phenotypes and cytokine release.

Register here

Meet regulatory compliance for biopharma with new mass spec software solutions

Friday, May 21, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Learn how advanced security features and built-in technical controls minimize security risks when applied to workflows for the analysis of intact proteins, protein digests and released glycans, by enabling setup of user roles, user permissions, audit trails, checksums, and secure content management across all software modules.

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Understanding the biological complexity of tissues with integrated imaging and analysis

Tuesday, May 25, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Dr. Stephanie Ling, Associate Principal Scientist at AstraZeneca, will explore how the integration of Imaging Mass Cytometry™ (IMC™) with other established molecular imaging modalities, including histology and mass spectrometry imaging, can enable insight into the biological complexity of tissues and pathophysiological processes.

Register here

Why functional assays are crucial for biopharmaceutical development success

Friday, June, 4, at 13:00 BST / 14:00 CEST / 08:00 EDT / 05:00 PDT

SVAR Life Sciences' Product Managers, Therese Segerstein, and Ali Qamar, will explain how functional assays can be used in safe and compliant biopharmaceutical development. They will focus on functional platforms for complement assessment and cell-based solutions for measurement and quantification of drug potency, detection of neutralizing antibodies (NAbs), and assessment of immunogenicity.

Register here

Optimize IP-RP method development for oligonucleotide analysis

Friday, June 4, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Ensuring high-quality oligonucleotides for therapeutic applications relies on robust analytical methods. In this webinar, hear from principal scientist Dr. Brook Koshel as she discusses method development considerations when selecting an appropriate ion-pairing agent. She will also share tips and tricks for developing efficient methods for ion-pair reversed-phase (IP-RP) analysis of oligonucleotides.

Register here

Register for the Biopharmaceuticals Webinar Series here>>

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.LC-MSLiquid Chromatography-Mass Spectrometry (LCMS) is a powerful analytical technique that combines the separation power of liquid chromatography with the detection capabilities of mass spectrometry. It is widely used for qualitative and quantitative analysis of complex mixtures in pharmaceuticals, proteomics, and environmental studies. Browse our peer-reviewed product directory to find the best LCMS systems, compare products, check reviews, and get pricing directly from manufacturers.

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