Biognosys’ Spectronaut™ Software Now Supports Thermo Scientific™ Proteome Discoverer™ Platform

27 Oct 2014
Kathryn Rix
Administrator / Office Personnel

Product news

Biognosys AG, a Swiss Proteomics Company, announced the new release of its Spectronaut™ software for analysis of Hyper Reaction Monitoring (HRM) data that will now support spectral library generation from the Thermo Scientific™ Proteome Discoverer™ platform.

From August 2013 Spectronaut™ software supports the analysis of DIA data generated on the Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer. In April 2014 spectral library generation capability based on MaxQuant search results was incorporated into the software. With the current Spectronaut™ release Biognosys enables Thermo Scientific™ customers to automatically generate spectral libraries from Proteome Discoverer™ search results.

HRM-MSTM is a targeted proteomics technology developed by Biognosys that is based on data-independent acquisition (DIA) performed on new generation mass spectrometric systems. With Biognosys’ Spectronaut™ software HRM enables reproducible and accurate quantification of 1000s of proteins in a single instrument run. The powerful principle behind Spectronaut™ is the integration of the software algorithms with a reagent kit – HRM Calibration Kit – that provides optimal customized parameter calibration and quality control: crucial steps for quantitation accuracy and reproducibility.

Spectronaut™ software is free for academic researchers who can obtain a software license at Biognosys’ online shop (academic e-mail account is required). Industry researchers are welcome to submit a Spectronaut™ order inquiry to order@biognosys.ch. Customers without an access to a state of the art mass spectrometer can benefit from Biognosys’ Proteome-SEQ™ discovery service that is based on the HRM-MS™ technology.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.