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BioFocus Launches Four Compound Libraries Targeting Kinases and Protein-Protein Interactions

12 Apr 2010
Sarah Sarah
Marketing / Sales

Product news

BioFocus announces the launch of four biologically targeted libraries. These new libraries contain novel, drug-like compounds that specifically target kinases and protein-protein interactions. BioFocus’ three new SoftFocus® kinase libraries (SFK61, SFK62 and SFK63) target either the hinge region, allosteric sites or novel binding modes. The SFK collection has been independently determined to have the greatest population of kinase-like molecules available for screening.

BioFocus’ second Helix Mimetic library (HM02) is based on a novel structure that interacts with protein helices. This library is designed to inhibit protein-protein interactions, but can also target other helical recognition motifs such as the pore region of ion channels.

“2010 marks the 11th year of BioFocus’ commitment to producing leading compound libraries for the discovery sector” said Richard Gordon, Senior Director, Sales and Marketing. “Innovative design and compound novelty ensure we provide our clients with the highest chance of success.”

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.

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