BioFocus, in Collaboration with the UCL Institute of Neurology, Receives Rapid Response Innovation Award from The Michael J. Fox Foundation

24 Jun 2013
Sarah Thomas
Associate Editor

Product news

BioFocus announced today that it has received a Rapid Response Innovation Award from The Michael J. Fox Foundation for Parkinson’s Research, a not-for-profit organization focused on developing therapies for Parkinson’s disease. BioFocus will use the investment to develop a high-throughput, high-content assay platform to support the discovery of targets and agents that break the pathogenic loop between glucocerebrosidase (GBA) and α-synuclein, considered to be a major mechanism leading to Parkinson’s disease.

The project is further supported by a new collaboration between BioFocus and Professor Tony Schapira, Institute of Neurology, University College London, a renowned medical researcher in Parkinson’s disease.
Prof. Tony Schapira commented: “The link between mutations in the GBA gene and Parkinson’s disease has been affirmed by multiple clinical studies. The development of a disease-relevant cell model system to support drug discovery on this mechanism will be a critical asset to the Parkinson’s disease research community.”

Prof. Julie Frearson, Senior Director Scientific Alliances and Translational Research, BioFocus, said: “We are delighted and honored to receive this grant. This funding will allow BioFocus to continue tackling novel and challenging therapeutic mechanisms in Parkinson’s disease.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Parkinsons DiseaseNeuroscienceNeuroscience research investigates the neurological mechanisms underlying behavior, neurodegenerative diseases, and other brain conditions. Learn about the innovative technologies for bioimaging, electrophysiology, cell culture, chromatography and other techniques used in this field.NeurobiologyNeurobiology studies the biology of the nervous system, including the structure and function of neurons, glial cells, and their interactions. It is a key field in understanding neurological disorders such as Alzheimer�s, Parkinson�s, and schizophrenia. Research in neurobiology is essential for developing therapies for these conditions. Browse our peer-reviewed product directory to find the best neurobiology research tools, compare products, check reviews, and get pricing directly from manufacturers.
BioFocus, in Collaboration with the UCL Institute of Neurology, Receives Rapid Response Innovation Award from The Michael J. Fox Foundation