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Bio-Rad’s Gene Pulser MXcell Electroporation System Guides Are Now Available

Bio-Rad
17 Jan 2008

Product news

Bio-Rad Laboratories, Inc., a multinational manufacturer and distributor of life science research and clinical diagnostic products, today announced two new product guides for its Gene Pulser MXcell™ electroporation system. The first product guide (bulletin 5640) is designed to assist scientists using the pre-set protocols in order to quickly optimize electroporation conditions. The bulletin contains detailed information for the MXcell’s preset protocols as well as information on a Decision Tree that aids in protocol selection. The second is an ordering guide (Bulletin 5598) that itemizes systems features, specifications and other information needed to order the MXcell system. The guides may be downloaded via the article webpage.

About the Gene Pulser MXcell Electroporation System
The Gene Pulser MXcell electroporation system is fully programmable and can deliver up to 24 different electroporation protocols in a single 96-well plate in two minutes or less. Unlike other instruments in which scientists may not be able to fine tune their system to get higher efficiencies, the MXcell system paired with the Gene Pulser electroporation buffer provides researchers a way to quickly optimize electroporation conditions to maximize the use of their cells and samples. The system can also be used as a rapid screening tool for the delivery of siRNA into any type of mammalian cell line.

The MXcell system features disposable 12-, 24- and 96-well plates offering options for high-throughput, replicated optimization, as well as multiple lab-scale transfections in a single plate. The software has gradient programming and pre-set optimization protocols for rapid plate set-up.

Target customers for the system are researchers at all levels in molecular biology laboratories in academia, core laboratories, and biotechnology, and pharmaceutical companies. At half the list price of other systems, the MXcell system enables scientists to conduct research on more medically relevant cells including stem cells.

About Electroporation
Electroporation is a valuable tool for nucleic acid delivery because it can be used for a wide variety of cell types. Along with a general movement in the scientific community to use more medically relevant cells, new tools for electroporation have become necessary as more scientists optimize delivery of siRNA, plasmids, or other molecules into mammalian cells, in particular, primary cells and those cells that are difficult to transfect.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Bio-Rad’s Gene Pulser MXcell Electroporation System Guides Are Now Available