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Bio-Rad Introduces C1000 Touch™ Thermal Cycler

Bio-Rad
3 Jul 2011
bridget bridget
Laboratory Director

Product news

Bio-Rad Laboratories, Inc. introduces the C1000 Touch thermal cycler, a PCR instrument that combines the high thermal performance and advanced features of the C1000™ thermal cycler with a new large color touch screen.

The C1000 Touch thermal cycler is ideal for large high-throughput labs, core facilities, and GLP labs that value fast turnaround time, flexibility, and adjustable throughput.

Bio Rad developed touch-screen navigation for the C1000 Touch thermal cycler so that researchers are able to edit, run, and save protocols with ease. Protocol Autowriter, which creates a protocol in three easy steps, is accessible from the home screen of the C1000 Touch thermal cycler.

A new 96–deep well block that can hold 0.2 or 0.5 ml tubes for reaction volumes over 50 µl (up to 125 µl) was developed for the C1000 Touch (as well as the C1000 and S1000™ thermal cyclers). The large reaction volume is useful for sample preparation upstream of applications such as next-generation sequencing using emulsion PCR and microarray library amplification.

With the C1000 Touch thermal cycler, PCR is:

• Easier — The large color touch screen and navigation offer intuitive programming and allow runs to begin in as few as three screen touches.

• Faster — The reduced-mass blocks shorten run times, and the thermal gradient allows for reaction optimization in a single run.

• Smarter — The system can adjust throughput by accommodating interchangeable 96-well, dual 48-well, and 384-well blocks, and it can be upgraded to real-time PCR.

To learn more about the C1000 Touch thermal cycler, visit the company article page.

Links

Bio-RadCompany website

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PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.

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