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Bio-Rad extends range of Foresight Pro prepacked chromatography columns for biotherapeutic production

Bio-Rad

Foresight Pro 45 cm ID column provides a convenient and reliable solution for purification of biomolecules in downstream bioprocessing

8 Jan 2025

Product news

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, has announced the launch of Foresight™ Pro 45 cm inner diameter (ID) chromatography columns, designed to support downstream process-scale chromatography applications across different stages of biological drug production.

Expanding on Bio-Rad’s portfolio of Foresight Pro columns with inner diameters ranging from 5 to 33 cm, the new, larger 45 cm ID Foresight Pro Column offers biopharma manufacturers an easily integrated solution for downstream purification of biomolecules, including vaccines, antibodies, and recombinant proteins. Foresight Pro Columns are manufactured and packed in a controlled ISO Class 7 cleanroom, providing good manufacturing practice (GMP) ready columns. The standardized design and format, in a range of diameters and bed heights, offer a convenient and reliable solution, packed with either CHT™ Ceramic Hydroxyapatite Media Type I, Type II, or XT. Bio-Rad’s CHT Media is a rigid mixed-mode support media for biomolecule purification. CHT’s unique composition, Ca10(PO4)6OH2, allows biomolecules to interact with the media by means of metal affinity interactions via calcium atoms and/or cation exchange interactions via phosphate groups.

“Building upon the successful reception of our initial range of 5 to 33 cm ID columns launched in 2022, the new 45 cm ID Foresight Pro Column is Bio-Rad’s answer to customers' requests for larger columns,” said Diab Elmashni, Director, Process Chromatography Business at Bio-Rad Laboratories. “These columns are unique in the market, as they are packed with a single lot of Bio-Rad’s CHT Media — other suppliers may combine different batches of our resins when packing columns. Thus, Bio-Rad’s Foresight Pro Columns are unique, single-source solutions that provide superior technical, application, and product support benefits to the biopharmaceutical industry.”

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.biopharmaceutical manufacturingChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.VaccinesSLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations. BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.

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Bio-Rad extends range of Foresight Pro prepacked chromatography columns for biotherapeutic production