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Biametrics Launches b-screen® Microarray Screening Device

19 Mar 2014
Sarah Thomas
Associate Editor

Product news

Biametrics GmbH, specializing in label-free analytical solutions for life science and diagnostics applications, today announced the launch of its b-screen® label-free microarray screening device in European markets. The device is an analysis tool for microarrays in the standard microscope format allowing the detailed studies of biomolecular interactions. Current applications include bioanalytics, drug discovery, production and quality control. Based on the same technology, the company develops b-portable®, a point-of-care device for early cancer and infection detection.

b-screen® is able to handle different sample types like body fluids (e.g. serum or whole blood) and other relevant complex matrices such as cell culture medium. Kinetic data can be obtained for almost any kind of biomolecular interaction such as for protein/protein, peptide/protein and small molecules/protein.

b-screen® features

b-screen® provides a label-free read-out of up to 10,000 spots per square centimeter. It utilizes a precise and automated microfluidics system for incubation of the microarray with the sample of interest. The device can be used with multiple array layouts (highly scalable), uses glass or plastic type substrates and is compatible with almost any common microarray printer. The high-throughput analysis is characterized by a high time resolution (no scanning) at low noise of the optical readout. No fluorescence labels are needed, which leads to assay conditions as close as possible to the in-vivo situation combined with minimal sample pre-treatment and minimized reagent consumption.

Gain additional information on kinetics and thermodynamics

“With b-screen® users are able to easily transfer existing microarrays directly into a label-free assay format thus gaining additional information on kinetics and thermodynamics at high precision and reliability,” says Günther Proll, Managing Director of Biametrics. “The device allows very low cost high-throughput screening and the applications we have established demonstrate excellent performance and outcome characteristics. We believe b-screen® provides key advantages over current options like surface plasmon resonance (SPR)”.

Biametrics will present its b-screen® system at Analytica 2014 in Munich, Germany.

Tags

High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.MicroanalysisScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.analyticaAnalytica is a leading international trade fair for laboratory technology, analysis, and biotechnology, showcasing innovations and solutions in the scientific community. Stay updated with the latest trends and products in the industry.

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Biametrics Launches b-screen® Microarray Screening Device