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Beckman Coulter Workstation Automates Antibody Cocktail Preparation

Beckman Coulter Diagnostics
26 Jan 2010
Sarah Sarah
Marketing / Sales

Product news

The Beckman Coulter Antibody Cocktail Preparation workstation automatically combines antibodies and staining dyes from individual vials into tubes or vials staged on the company’s Biomek* NXp deck. Automating the multi-color flow cytometry analysis preparation process eliminates costly errors associated with manual preparation and improves efficiency. Complex multi-reagent, multi-panel antibody staining cocktails** are prepared with precision and accuracy.

Antibodies can be directly aliquoted into single 12 x 75 mm sample tubes in 96-tube racks. Cocktails can also be produced in bulk in 4 mL dark color vials. Additional output formats may be developed upon customer request.

Built-in temperature control and light and evaporation protection reduce factors that could potentially affect fluorochrome-conjugated antibody stability

An intuitive software interface presents easy-to-use features for antibody panel definition and management. It simplifies daily operation and data management with multiple report options and formats. The software package also controls access through the user account management function.

“Automating this important and complex process will provide researchers with antibody panels that they can depend on,” said Graham Threadgill, director, Life Science Automation. “This new workstation will enable precise and cost-effective identification of targets.”

Research flow cytometry applications requiring multiple panels of staining cocktails with multiple antibodies or staining dyes, for use in leukocyte classification and in studies of vaccine efficacy and complex immune response, are becoming increasingly popular. By automating the cocktail preparation process, costly human errors can be avoided. Additionally, antibody names, lot numbers and consumption levels are automatically tracked and stored in a database.

*Trademarks are property of their respective owners.
**For Laboratory Use Only: Not for use in diagnostic or therapeutic procedures.

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Beckman Coulter DiagnosticsCompany website

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Robotic WorkstationsRobotic workstations are automated platforms enabling the user to perform high-throughput, multi-application processes, from sample preparation tasks such as PCR set-up, DNA purification and NGS library preparation, to integrated sample prep and analysis workstations. Automation makes processes consistent, fast, precise and fully walk-away. Find the best robotic workstations in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Beckman Coulter Workstation Automates Antibody Cocktail Preparation