Beckman Coulter Life Sciences Launches New Family of FFPE Reagent Kits

Single chemistry system extracts total nucleic acid, DNA and/or RNA from single FFPE tissue sample

23 Jan 2018
Frankie MacDonald
Administrator / Office Personnel

Industry news

Beckman Coulter Life Sciences has launched a family of FormaPure reagent kits for extracting nucleic acid from often challenging formalin-fixed, paraffin-embedded (FFPE) tissues. FormaPure reagent kits represent a single chemistry system designed and optimized for use in next-generation sequencing (NGS) and other downstream applications, including qPCR/ddPCR/PCR. The family of reagent kits is made up of FormaPure Total for total nucleic acid isolation, FormaPure DNA for DNA isolation and FormaPure RNA for RNA isolation.

“Maximizing sample integrity, yield and purity from FFPE samples is required to minimize the risk of losing critical genetic information,” said Tom Curtis, director of genomics marketing, Beckman Coulter Life Sciences. “Our FormaPure reagent kits provide researchers flexible, scalable solutions that generate consistent results while maintaining higher-integrity nucleic acids to support the improved sensitivity of NGS applications.”

Read our ‘Challenging Samples in Cancer Research’ series to learn more about how FFPE is used by researchers around the world >>

NGS performance often starts with RNA integrity. FormaPure chemistry, when compared to similar, “industry-leading” kits currently in use, retains the best possible RNA integrity because the extraction chemistry is optimized for achieving the best results from even the most challenging FFPE tissues. Better yet, the chemistry system also provides significantly more fusion calls and fusion reads than other FFPE extraction kits, and at a fraction of the price.

“Losing critical data during extraction workflows can significantly impact discovery,” added Curtis. “In the end, researchers only need as much nucleic acid as their library prep protocol calls for. It’s essential to start with the highest-quality, not necessarily the most, data-rich samples one can obtain through extraction.”

FormaPure Total, FormaPure DNA and FormaPure RNA are the newest additions to the Beckman Coulter Life Sciences growing portfolio of Agencourt reagent kits for nucleic acid isolation, purification and cleanup.

Do you use FormaPure DNA in your lab? Write a review today for your chance to win an iPad or a $400 dollar amazon voucher

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DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.FFPEFormalin-fixed paraffin-embedded (FFPE) tissues are commonly used in medical research, particularly in histology and cancer studies. The preservation process allows long-term storage of tissue samples for later analysis. Explore FFPE research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.