Beckman Coulter Life Sciences and HSE•AG announce new partnership

This partnership aims to redefine nucleic acid quantification and purification by leveraging liquid handling automation

11 Sept 2025

Industry news

Beckman Coulter Life Sciences, a Danaher company and global leader in laboratory automation and innovation, is redefining nucleic acid quantification through a strategic collaboration with Hombrechtikon Systems Engineering•AG (HSE•AG), a Swiss provider of customized automation and engineering solutions for the life sciences and diagnostics sectors.

Biomek i7 automated workstation

This partnership updates and miniaturizes traditional nucleic acid quantification, powered by an automation-first approach that integrates high-throughput liquid handling directly into molecular biology workflows. By streamlining critical processes—from normalization to yield characterization—it bridges existing workflow gaps and empowers real-time, data-driven decision-making within a unified platform. Automated pipetting is seamlessly embedded as a functional extension of the system’s ecosystem, driving efficiency and precision at scale.

Integrating the HSE eviDense UV Photometer directly onto the deck of Biomek i-Series automated workstations from Beckman Coulter Life Sciences enables real-time absorbance measurements seamlessly within the liquid handling process to deliver faster, more efficient results while eliminating manual intervention. This technique precisely measures nucleic acid concentration and purity at 260/280 and 260/230 nanometer ratios. The non-destructive analysis allows valuable sample volume to be immediately recovered or advanced through the workflow based on user needs. Designed as a drop-in replacement, the instrument integrates effortlessly into established workflows and protocols, using proven methods to automate and close existing process gaps.

eviDense UV Photometer

eviDense UV Photometer

“Time is the most critical facet in the laboratory today, and we’re always examining workflows to see how we can help laboratories achieve results faster with greater accuracy,” said Ewan Grant, Senior Director of the Biotech Business Unit at Beckman Coulter Life Sciences. “This collaboration is a major step forward in advancing nucleic acid quantification. By enabling this workflow to be executed through a liquid handler, we’re uniquely able to help laboratories maximize walk-away time for both extraction and NGS library preparation, empowering researchers to get the answers they seek faster.”

The partnership also simplifies fluorometric analysis of nucleic acid quantification, delivering results in as little as 20 minutes for 96 samples. By integrating the HSE eviFluor Duo microcuvette-based fluorometer on the deck of a Biomek i-Series Automated Workstation from Beckman Coulter Life Sciences, laboratories gain access to a fully automated, end-to-end sample preparation solution. This system enables real-time data generation for immediate, decision-based pipetting—dramatically increasing speed and precision while eliminating manual, error-prone and time-consuming steps.

“The collaboration between Beckman Coulter Life Sciences and HSE marks a significant advancement in lab automation,” said Konstantin Lutze, Chief Technology Officer at HSE. “With the integration of the eviDense UV Photometer and the eviFluor Duo Fluorometer into the Biomek i5 and i7 workstations, both absorbance and fluorescence measurements are performed fully automatically within the liquid handling workflow. This enables highly efficient nucleic acid quantification while enhancing data integrity and measurement consistency. By eliminating manual interactions, the risk of user-induced errors is minimized. Together, we support laboratories in achieving greater efficiency, reliability, and scalability through fully integrated, automated workflows.”

These two innovations empower research laboratories to accelerate drug discovery, reduce manual workload, and improve data reliability across genomic workflows, bringing researchers one step closer to the answers that matter most.

Product not intended or validated for use in the diagnosis of disease or other conditions.

Want the latest science news straight to your inbox? Become a SelectScience member for free today>>

Links

Tags

Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA QuantificationDetection and quantification of nucleic acids is important in molecular biology, cloning, expression, forensics and clinical diagnostics. Nucleic acids can be detected by labeling with colorimetric, fluorescent or radio labels and using in situ hybridization kits to identify specific sequences. Multiple nucleic acids can be detected and quantified at once using RNA / DNA detection beads or RNA / DNA microarrays. Find the best DNA / RNA Quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.