Beckman Coulter Life Sciences accelerates high-throughput genomic sample preparation

New Biomek Echo One System reduces workflow time from hours to minutes

2 Jul 2024

Product news

 Biomek Echo One System

The new Biomek Echo One System from Beckman Coulter Life Sciences

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, accelerates high-throughput genomic sample preparation workflows to deliver results faster with the launch of its Biomek Echo One System. The new solution provides versatile integrated acoustic liquid handling options for applications in genomic workflows, including high-throughput isothermal DNA assemblies and NGS library sample preparations.

The Biomek Echo One System combines two Beckman Coulter Life Sciences core liquid handling instruments: the Echo 525 Acoustic Liquid Handler and the Biomek i7 Hybrid Workstation, which can be integrated with existing laboratory automation instrumentation. The new platform can execute library preparation steps such as extraction, fragmentation, ligation, normalization and pooling along with requisite actions such as centrifugation, shaking and thermal incubation in one automated method.

Laboratories are now empowered to achieve ultimate workflow flexibility, from standalone PCR reaction setups to a fully executed NGS library preparation protocol using all of the integrated devices. The intuitive system requires minimal user training to ensure laboratory staff can unleash the benefits immediately. Users can easily scale up walk-away time and throughput to adapt to changes in workflow demands and needs, creating a future-proof solution that can grow with laboratory needs and complexities.

The Echo 525 Acoustic Liquid Handler uses sound energy to move precise, nanoliter-scale droplets in a combinatorial fashion that significantly exceeds traditional sample transfer speeds for workflows such as DNA assembly, including pooling and normalization steps. Using traditional liquid handlers, laboratories have reported eight-hour workflows slashed to just 30 minutes when performed on an Echo 525 liquid handler with seamless pass-offs to the Biomek Workstation for further downstream execution of the workflow.

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Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GenomicsGenomics is the study of genomes, focusing on the sequencing, analysis, and interpretation of genetic material. It is key in understanding genetic diseases, evolutionary biology, and personalized medicine. Techniques like next-generation sequencing (NGS) are commonly used in genomics research. Browse our peer-reviewed product directory to find the best genomics tools, compare products, check reviews, and get pricing directly from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Genomic DNA