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Base editing: Impact on cell therapy and how to access it

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Join us Thursday, November 5, to learn how to introduce base editing technology into your cell therapy pipeline

20 Oct 2020
Tom Casburn
Associate Editor

Expert insights

Dr. John Lambourne, R&D manager, Horizon Discovery

Therapeutic developers are on the pinnacle of revolutionizing cell therapies with cutting-edge technologies for editing the genome. However, classical genome editing techniques can suffer from questionable safety profiles when utilized for the simultaneous modification of multiple loci. An alternative, safer technology is base editing and this webinar will introduce the concept and applications of the technology to the cell therapy community.

In this SelectScience webinar, Dr. John Lambourne, R&D manager in the therapeutics applications arm of the Horizon Discovery Pin-point™ base editing team, will cover the advantages inherent in utilizing base editing technology and the possible impact this could have on the development of cell therapies. Lambourne will also present some initial data generated during the development of Horizon's Pin-point™ base editing system and describe how organizations can access the system.

Register now

The webinar will cover:

  • What is base editing?
  • How will it and other safe gene engineering technologies impact the effectiveness of cell therapies?
  • How can it be accessed and introduced into your cell therapy pipeline?

Scientists and laboratory professionals working in the following areas will be interested in this webinar:

  • Cell/gene therapy development
  • Gene engineering/gene editing
  • CAR-T researchers, senior scientists, laboratory heads, group leaders, biopharma

The live webinar takes place on Thursday, November 5 at:

  • 16:00 GMT
  • 17:00 CET
  • 11:00 EST
  • 08:00 PST

SelectScience runs 10+ webinars a month across various scientific topics, discover more of our upcoming webinars>>

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Cell TherapyCell therapy involves using living cells to treat diseases, often by replacing damaged cells or stimulating regeneration. Stem cell therapy and CAR-T cell therapy are examples of cutting-edge treatments in regenerative medicine and cancer immunotherapy. Browse our peer-reviewed product directory to find the best cell therapy tools, compare products, check reviews, and get pricing directly from manufacturers.Gene EditingGene editing is the precise alteration to an organism's DNA, with CRISPR being the most well-known technique. It is used in a wide range of applications, including the development of disease models and gene therapy, and crop improvement. Browse our peer-reviewed product directory to find the best gene editing solutions, compare products, check reviews, and get pricing directly from manufacturers.Genome EditingGenome editing involves altering the DNA of an organism, which holds promise for disease treatment, agriculture, and gene therapy. Techniques like CRISPR-Cas9 are revolutionizing this field, enabling precise genetic modifications. Explore genome editing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Genetic EngineeringWebinar

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Base editing: Impact on cell therapy and how to access it