SelectScience
Join Free
Accelerating Science
NewsLife Sciences

Axela Biosensors Unveils the dotLab™ System

Axela Biosensors Inc.
15 May 2006

Product news

Axela Biosensors, Inc. today announced the successful preview of its new dotLab System at Biosensors 2006, The Ninth World Conference on Biosensors, held in Toronto on May 10-12.

The dotLab System is an open assay platform that enables real-time monitoring of protein interactions. Axela plans to launch the dotLab System in the fall of 2006.

“There is a strong need for a platform with the capabilities of the dotLab System that can address the large, underserved market for protein detection,” said Rocky Ganske, President and CEO of Axela Biosensors. “In addition, the translational research studies that health researchers will perform using the dotLab System are a natural precursor to Axela’s planned move into the larger clinical diagnostics market.”

The core of the dotLab System is Axela’s Diffractive Optics Technology (DOTTM). This novel biosensor technology enables researchers to rapidly identify and quantify therapeutic and clinically relevant protein biomarkers without the need for fluorescent tags. The dotLab System will also allow scientists in academia and pharmaceutical research to rapidly detect and understand molecular interactions at their bench in real-time. Initial applications for the dotLab System will focus on immunoassays and their development, and include rapid reagent characterization, antibody pairing and cross reactivity studies. These capabilities greatly accelerate the optimization and performance of high sensitivity multiplexed immunoassays in complex media.

Links

Axela Biosensors Inc.Company website

Tags

AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

Related articles

Axela Biosensors Unveils the dotLab™ System