Automated SDS-PAGE in 1 minute per sample – ScreenTape® for rapid protein electrophoresis and analysis

6 May 2009
Kerry Parker
CEO

Product news

At the recent BioProcess International (BPI) congress in Dusseldorf, Lab901 unveiled its new ScreenTape P200 product for rapid SDS-PAGE and analysis. Generating results in only 1 minute per sample, the P200 protein system extends the use of Lab901’s existing bench-top TapeStation® instrument which has already started to make a global impact in the DNA market for PCR diagnostics.

Used with the TapeStation, ScreenTape P200 combines gel loading, electrophoresis, imaging and analysis. Results include a gel image, electropherogram, molecular weight determination and % purity - all generated in 60 seconds per sample. There is no need to prime chips, stain / de-stain gels, image gels or annotate gel images when using the ScreenTape System. ScreenTape can run just a few samples, leaving unused lanes available for future experiments and reducing the waste commonly encountered with chip-based systems and pre-cast gels.

‘We are very excited about the launch of ScreenTape for protein analysis’ commented Richard Rowling, Lab901’s Sales & Marketing Director. ‘The combination of convenience and speed means that scientists can now move more rapidly between steps in their expression / purification workflows, saving time and money.’

‘The response from scientists expressing and purifying recombinant proteins or MAb’s has been tremendous at the BPI meeting’ said Dr. Ken Macnamara, Lab901’s Head of Science. ‘There is a real appetite for speed and automation in the BioPharma industry. Our poster, describing rapid At-line monitoring of MAb production, was very well received’ he added.

Links

Tags

ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.