Automated iPSC culture with machine learning-enabled cell passaging control and automated differentiated cell detection

28 Nov 2025

Discover how the CellXpress.ai® Automated Cell Culture System transforms iPSC maintenance and expansion into a fully automated, walk-away workflow. This application note showcases a machine learning–enabled solution that monitors colony confluency and differentiation in real time, triggering automated passaging or excluding wells based on user-defined thresholds. By integrating liquid handling, imaging, and intelligent decision-making, the system reduces manual workload, improves consistency, and preserves stem cell quality.

Ideal for scaling up stem cell research, this approach ensures reproducibility, saves time and reagents, and empowers scientists to focus on discovery, not routine cell culture.

CellXpress.ai Automated Cell Culture System

Molecular Devices®

The CellXpress.ai™ Automated Cell Culture System is an AI-driven cell culture innovation hub that gives your team total control over demanding cell culture feeding and passaging schedules—eliminating time in the lab while maintaining a 24/7 schedule for growing and scaling multiple stem cell lines, spheroids, or organoids.

(0)

Links

Tags

Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Artificial Intelligence / Machine LearningArtificial intelligence (AI) and machine learning (ML) are transformative technologies used to analyze complex data, identify patterns, and make data-driven predictions across diverse scientific fields. Automate the analysis of large or complex data sets using AI algorithms and leverage machine learning models to improve diagnostics, accelerate drug discovery, and refine experimental design. Discover the best AI/ML software, platforms, and analytical tools in our peer-reviewed product directory: compare features, read customer reviews, and request pricing directly from manufacturers.