Asia Flow Chemistry System Ideal for Biocatalytic Applications

27 Sept 2012

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Researchers in the Department of Organic Chemistry at the Chemistry Institute of the Federal University of Rio de Janeiro are taking advantage of the modular Asia flow chemistry system from Syrris to develop biocatalyzed continuous flow reactions.


Professor Dr Rodrigo Souza, Associate Professor in Organic Chemistry, explained: “Our department is dedicated to teaching and research into organic chemistry, and wanted a continuous flow system to perform biocatalytic reactions. We needed a flow chemistry system that would enable us to load catalysts onto a packed bed easily, and the Asia system has proved ideal.”

“We purchased the Asia system a year ago, and found it easy to implement in our laboratory. It is a very user-friendly system, and the wide range of flow rates offered by the Asia Pump is a big advantage. We also have the capability to load the solid phase column reactors with our own catalysts, which is another great benefit. The system is running seven days a week, and is so popular that people are queuing up to use it. The Asia system helped us to become the first group at the University – and in Brazil – to develop biocatalyzed continuous flow reactions, and we now plan to buy another similar system to help meet the needs of our laboratory.”

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.PumpsLaboratory pumps are devices used to move liquids and gases by vacuum or positive displacement. The pressures/vacuums generated are determined by the type of pump used. High vacuum pumps include diffusion, ion, roots and turbopumps; for primary/medium vacuum applications see rotary vane pumps, scroll & diaphragm pumps. For the positive displacement of liquids explore a range of syringe and peristaltic pumps, as well as fluid aspirators. Discover the best pumps in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow ChemistryFlow chemistry describes a chemical reaction being carried out continuously rather than in a batch process. The reagents are pumped through a pipe and forced together at a mixing junction, where they are allowed to combine until the reaction is stopped.Biocatalytic Reactions
Asia Flow Chemistry System Ideal for Biocatalytic Applications