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Applied Biosystems introduces new TargetSeq™ Resequencing System for high throughput projects

Thermo Fisher Scientific
9 May 2006
Kerry Parker
CEO

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The Applied Biosystems TargetSeq™ Resequencing system is a new software system for project-specific optimisation of high throughput resequencing of smaller and targeted genomic regions, using the Applied Biosystems 3730 and 3730xl DNA Analyzers.

The TargetSeq system features a fast-run software module for the sequencing of individual exons or other small DNA fragments and it can produce 200 to 400 base pair reads in 20 minutes or less. This system increases the number of bases read by the 3730 Analyzer series to more than 2.8 megabases or 6912 samples (72 runs) per day, dramatically increasing the throughput of high workload resequencing projects in cancer and medical research.

TargetSeq software is easy to install and uses existing hardware, software and reagent components on the 3730 series analysers. It includes a new version of the KB™ Basecaller software optimised for heterozygote or mixed base detection. This latest advance in DNA sequencing means that the 3730 Analyzer series and TargetSeq software provide the only high throughput genetic analysis system with the flexibility to run both long and short fragments.

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Applied Biosystems introduces new TargetSeq™ Resequencing System for high throughput projects