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Anagnostics Hybcell Technology to be used for Drug Development

Anagnostics Bioanalysis
9 Feb 2012
Sonia Nicholas
Managing Editor and Clinical Lead

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Anagnostics has announced that it is to form a strategic partnership with the Viennese company, Vela Laboratories, to offer hybcell technology to biotech and pharma customers under good manufacturing practice (GMP) conditions.

Anagnostics Bioanalysis focuses on development and production of systems and tests for analytics in drug development and clinical diagnostics. Its patented hybcell technology combines DNA- and protein tests on the same device (hyborg), and enables innovative and efficient diagnostic solutions for the rapidly growing demand driven by personalized medicine.

Vela Laboratories is an internationally active GMP certified contract research/analytics laboratory. The company offers a broad portfolio of analytical methods, especially for characterisation of proteins. It also offers customer specific analytical services.

The agreement between Vela Laboratories and Anagnostics will enable them to collaborate in the fields of analytical services, as well as marketing and sales for drug discovery units.

‘The fast growing demand in the field of Biosimilars - Comparability Testing results in a need for creative business models. Vela obtained international reputation within the market for complete characterisation of Biopharmaceuticals, Biologics and Biosimilars and is among the top tier suppliers of ICH Q6B conform protein analytics. Anagnostics hybcell technology offers totally new analytical solutions, which we want to offer our customers. Together we can serve our customers more efficiently and comprehensively’ comments Dr. Markus Fido, CEO of Vela Laboratories, the decision of his company.

‘Synergies stemming from Anagnostics’ innovative analytical approaches and the outstanding expertise of Vela Laboratories enable Anagnostics to speed up the market penetration in the field of drug discovery’, is highlighted by Christoph Reschreiter, CEO of Anagnostics Bioanalysis GmbH.

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Hybcell - DNA or protein microarray

Anagnostics Bioanalysis

Anagnostics' hybcell is the world's first DNA or protein microarray based on the use of cylinders instead of slides. hybcell technology is... KINETIC - by means of consecutive scans, FAST - with help of rotational sample agitation, FLEXIBLE - due to fixed starting temperatures, flexible temperature profiles and computer-controlled buffer exchange and EFFICIENT - by automated processing and electronically documenting of up to 96 samples in a single run.

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Hyborg - cylindrical DNA and protein analysis

Anagnostics Bioanalysis

Hyborg is a fully automated device for processing and analysing hybcells (cylindrical DNA and protein microarrays). Hyborg integrates thermocycler, hybridisation station and scanner into a single device. All processing steps - from temperature profiles or exchange of liquids to multi-color scanning - are computer-controlled and documented. Hyborg's concept of totally integrated automation guarantees maximum reproducibility of assays. Autonomous processing of up to 96 hybcells reduces hands-on-time to a minimum and provides maximum ease of use.

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Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.

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