Anachem Flexus - The First Automated Liquid Handler with Fully Integrated Centrifuge

8 Jan 2007

Product news

Anachem Flexus is a completely new automated liquid handling system that brings unique features to handle multiple applications, without user intervention. Its flexibility enables integration of a vast range of peripheral instruments to enable complete protocols to be fully automated.

Flexus is the only liquid handling system to incorporate an on-board centrifuge – perfect for procedures such as protein precipitation.

The Flexus centrifuge can be fully integrated into its deck or positioned alongside and accessed through an optional extended x-rail. It can accommodate two microplates, standard or deep well plates, or gel cards. A loading shutter opens and closes under software control, and an automatic homing position facilitates robotic access. Advanced safety features ensure that the unit stops if the rotor is unbalanced. With a Relative Centrifugal Force of 2000g and run times of 5 seconds to 9 hours, various samples and protocols can be handled efficiently.

This innovation brings full automation opportunities to an extensive variety of your applications, such as Protein Precipitation and blood typing. The control and elimination of potential for human error, enabled by Flexus, makes these methods more reproducible and efficient.

The specific Flexus DMPK pre-configured pipetting station puts the integrated high speed centrifuge to excellent use in fully automating traditional protein precipitation methods. The elimination of proteins from biological fluids is an important procedure in drug analysis, essential to avoid interference with downstream applications and analyses via LC/MS/MS. With Flexus DMPK, a 96 well plate can be prepared in less than 15 minutes, including addition of acetonitrile and centrifugation, without any human intervention.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.CentrifugesCentrifuges are used to separate particulates suspended in a liquid via the application of a centrifugal force including cells, macromolecules, nanoparticles and precipitates. Centrifuges come in three sizes: microcentrifuges, benchtop and floor-standing centrifuges, depending on the volume and number of samples that require separation. When choosing a centrifuge, consider its maximum separation power indicated by its relative centrifugal force (RCF) value. Low force centrifuges reach a maximum RCF of 8,000 g, high-force centrifuges can reach maximum RCF values of 80,000 g. For extremely high forces, consider ultracentrifuges (up to 800,000 g). Refrigerated and vacuum centrifuges also known as concentrators are available for more specialized applications. A range of volumes are available for centrifuge tubes and microfuge tubes, depending on sample sizes. Find the best centrifuges in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Anachem Flexus - The First Automated Liquid Handler with Fully Integrated Centrifuge