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An automated system for post-extraction clean-up by Gel Permeation Chromatography

Gilson, Inc.
2 May 2007
Kerry Parker
CEO

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Gilson, Inc., an industry leader in purification systems for HPLC and SPE, introduces a solution for automated post-extraction clean-up of interfering substances from environmental samples, food products and animal tissue by Gel Permeation Chromatography (GPC) prior to analysis by GC, GC/MS, HPLC or LC/MS. To improve the optimal analytical results, lengthen hardware life including column life and increase your analytical systems uptime, Gilson’s new automated system removes the interfering compounds after sample extraction and prior to analysis.

The Automated GX-271 GPC Clean-up System provides an affordable solution for laboratories performing residue analysis of complex matrices such as fatty foods, soils, sludge, animal and plant tissue. The system features a Direct Injection Module and a fraction collection valve located on the Z-arm, increasing efficiency by reducing sample carryover and post valve dead volume.

The Automated GPC system is fully controlled with TRILUTION® LC Software, a user-friendly, easy-to-use, flexible program that was specifically designed to meet the laboratory needs. The software features pre-programmed methods specific to GPC post-extraction clean-up processes.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Size Exclusion ChromatographySize exclusion chromatography (SEC) is a liquid chromatographic technique used to separate and identify molecules based on their size, including polymers, proteins, nanoparticles & nucleic acid. SEC is further subdivided into gel filtration chromatography (GFC) and gel permeation chromatography (GPC) when an aqueous or organic mobile phase is used respectively. HPLC-based SEC systems and columns are available for analytical separation alongside SEC spin columns or filters to prep samples for many protocols. Find the best size exclusion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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An automated system for post-extraction clean-up by Gel Permeation Chromatography