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AMSBIO offers fully characterized and annotated normal and disease-state Formalin-Fixed Paraffin-Embedded (FFPE) tissue blocks

AMSBIO
13 Jul 2021
Noorus Khan
Biomedical Scientist / Medical Lab Scientist

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AMSBIO has established a commercial biorepository and procurement network that includes a large selection of fully characterized and annotated Formalin-Fixed Paraffin-Embedded (FFPE) tissue blocks to help streamline your research.

Drawing upon decades of experience - AMSBIO is able to offer an extensive collection of frozen and paraffin-embedded (FFPE) human and animal tissue samples from normal and many diseased tissue types. All FFPE tissue blocks are processed using standard clinical procedures, under Institutional Review Board (IRB) approved protocols. Each tissue sample is pathologically verified and quality assessed by a board-licensed pathologist before being shipped with donor demographics and clinical details.

Characterized samples sets are now available and include many clinically relevant mutations and biomarkers, such as EGFR, PD-L1, KRAS, NRAS, MSI, MMR, and BRAF. In addition, comprehensively NGS characterized FFPE solid tumor tissues suitable for assay development, genotyping and identification of new mutational hotspots.

FFPE tissue blocks are an invaluable resource and can be supplied ready to use or can be tailored to suit your workflow and provided as slides, scrolls or array formats.

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Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. FFPEFormalin-fixed paraffin-embedded (FFPE) tissues are commonly used in medical research, particularly in histology and cancer studies. The preservation process allows long-term storage of tissue samples for later analysis. Explore FFPE research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

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