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AMSBIO Launches a New Range of Genetically Characterized FFPE Tissue Samples

AMSBIO
24 Feb 2014
Sarah Thomas
Associate Editor

Product news

AMSBIO has launched CancerSeq™ - a new range of genetically characterized FFPE tissue samples.

CancerSeq™ samples are prepared from genomic DNA extracted from the FFPE tumor tissues and validated by Next Generation Sequencing using Illumina’s TruSeq Amplicon - Cancer Panel (TSACP).Available as tissue slides and whole blocks, samples are delivered with the mutation and variation data for 48 cancer-related genes including BRAF, KRAS, EGFR, ALK and TP53.

Suitable for a range of applications

CancerSeq™ tissue samples provide researchers with the perfect medium for applications including validation of cancer marker mutation related drug candidates; companion diagnostic assay development ; cellular localization of tissue specific mRNA and protein expression; Comparison of the locations of novel genes in different tissues as well as in situ hybridization, immunohistochemistry, and in situ PCR experiments.


Clinical history data is provided

Available from several tumor tissue types, donor clinical history data is provided with each CancerSeq™ sample. In addition - AMSBIO offers custom services to characterize your specimens or selected samples from its biorepository of cancer and normal FFPE blocks.

Links

AMSBIOCompany website

Tags

Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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AMSBIO Launches a New Range of Genetically Characterized FFPE Tissue Samples